Accession No. | Name | Source / Entry Date | Species / Tissue | Cell Compartment | Methodology / Model Implementation |
1 | fig2_egfr | Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication ) / 2001-11-07 00:00:00 | Generic mammalian / Brain | Surface - Nucleus | Quantitative match to experiments, Hypothetical / Exact GENESIS implementation |
2 | fig3_CaMKII | Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication ) / 2001-11-07 00:00:00 | Generic mammalian / Neuronal | Synapse | Quantitative match to experiments, Qualitative / Exact GENESIS implementation |
3 | fig4_synapse | Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication ) / 2001-11-07 00:00:00 | Generic mammalian / Neuronal | Synapse | Quantitative match to experiments, Qualitative, Hypothetical / Exact GENESIS implementation |
4 | mkp1_feedback_ effects | Bhalla US et al. Science (2002) 297(5583):1018-23. ( peer-reviewed publication ) / 2001-11-07 00:00:00 | Generic mammalian / NIH 3T3 Expression | Surface - nucleus | Quantitative match to experiments / Exact GENESIS implementation |
8 | 3d_fold_model | Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication ) / 2001-11-08 00:00:00 | Generic mammalian / NIH 3T3 Expression | Surface - Nucleus | Quantitative match to experiments / Exact GENESIS implementation |
9 | MAPK_MKP1_ oscillation | Bhalla US, Iyengar R. Chaos (2001) 11(1):221-226. ( peer-reviewed publication ) / 2001-11-08 00:00:00 | Generic mammalian / NIH 3T3 Expression | Surface - Nucleus | Qualitative / Exact GENESIS implementation |
11 | NOS_Iwanaga | In-house. / 2001-11-12 00:00:00 | Rat; Mammalian / Neuronal; Expression in E.coli | Cytosol | Quantitative match to experiments / Exact GENESIS implementation |
12 | Stuehr_NOS | Santolini J. et al. J Biol Chem. (2001) 276(2):1233-43. ( peer-reviewed publication ) / 2001-11-12 00:00:00 | Generic mammalian / Neuronal ; Expressioned in E.coli | Cytosol | Quantitative match to experiments / Approximate implementation |
13 | PLCbeta1 | In-house
/ 2001-11-12 00:00:00 | Bovine; Mammalian / Brain - Neuronal; expressed in E.coli | Cell Membrane | Qualitative / Exact GENESIS implementation |
15 | sGC_Stone_ Marletta | Stone JR, Marletta MA. Biochemistry (1996) 35(4):1093-9. ( peer-reviewed publication ) / 2001-12-12 00:00:00 | Bovine / Lungs | Cytosol | Quantitative match to experiments / Mathematically equivalent |
16 | Synaptic_ Network | Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication ) / 2001-12-12 00:00:00 | Generic mammalian / Neuronal | Synapse | Quantitative match to experiments, Qualitative / Exact GENESIS implementation |
18 | Kuroda_GC | Kuroda S. et al. J Neurosci. (2001) 21(15):5693-702. ( peer-reviewed publication ) / 2001-12-24 00:00:00 | Generic mammalian / Neuronal | Synapse | Quantitative match to experiments / Exact GENESIS implementation |
19 | CondorelliGC | Condorelli P, George SC. Biophys J. (2001) 80(5):2110-9). ( peer-reviewed publication / 2001-12-25 00:00:00 | Generic mammalian / Pulmonary and vascular smooth muscle | Cytosol | Quantitative match to experiments / Mathematically equivalent |
20 | NOS_Phosph_ regulation | In-house / 2001-12-25 00:00:00 | rat; Mammalian / Brain - Neuronal; expressed in E.coli | Cytosol | Quantitative match to experiments, Qualitative / Exact GENESIS implementation |
23 | NonOsc_Ca_ IP3metabolism | Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication ) / 2002-01-07 00:00:00 | Generic mammalian / Brain - Neuronal | Cytosol | Quantitative match to experiments, Qualitative / Approximate implementation |
24 | Osc_Ca_ IP3metabolism | Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication ) / 2002-01-08 00:00:00 | Generic mammalian / Brain - Neuronal | Cytosol | Quantitative match to experiments, Qualitative / Approximate implementation |
25 | cAMP_pathway | Bhalla US Methods Enzymol. 2002;345:3-23). ( peer-reviewed publication ) / 2002-01-12 00:00:00 | Generic mammalian / Brain - Neuronal | Cell membrane + Cytosol | Quantitative match to experiments, Qualitative / Exact GENESIS implementation |
26 | PKC_turnover | In-house
/ 2002-01-22 00:00:00 | Generic mammalian / Brain - Neuronal | Cell membrane +Cytosol | Quantitative match to experiments, Qualitative / Exact GENESIS implementation |
27 | MAPK_osc | Boris N. Kholodenko Eur J Biochem. (2000) 267(6):1583-8). ( peer-reviewed publication ) / 2002-01-22 00:00:00 | Xenopus / Oocyte extract | Cytosol | Hypothetical / Mathematically equivalent |
28 | CO_activation_ of_GC | In-house / 2002-01-22 00:00:00 | Bovine / Lungs | Cytosol | Quantitative match to experiments, Qualitative / Exact GENESIS implementation |
29 | Kierzek_LacZ | Kierzek AM. et al. J Biol Chem. (2001) 276(11):8165-72. ( peer-reviewed publication ) / 2002-01-28 00:00:00 | E. Coli / - | Internal | Qualitative / Approximate implementation |
30 | Huang_Ferrell_ MAPK | Huang CY and Ferrell JE Jr. Proc Natl Acad Sci U S A. (1996) 93(19):10078-83 ( peer-reviewed publication ) / 2002-01-31 00:00:00 | Xenopus / Oocytes extract | Cytosol | Quantitative match to experiments / Approximate implementation |
31 | NonOsc_Ca_ IP3metabolism | Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication ) / 2002-04-03 00:00:00 | Generic mammalian / Brain - Neuronal | Cytosol | Quantitative match to experiments, Qualitative / Exact GENESIS implementation |
32 | Osc_Ca_ IP3metabolism | Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication ) / 2002-04-03 00:00:00 | Generic mammalian / Brain - Neuronal | Cytosol | Quantitative match to experiments, Qualitative / Exact GENESIS implementation |
33 | CaMKII | William R. Holmes J Comput Neurosci. (2000) 8(1):65-85 ( peer-reviewed publication ) / 2002-08-21 00:00:00 | Generic mammalian / Brain - Neuronal | Synapse | Qualitative / Approximate implementation |
34 | cGMP_regulation | In-house
/ 2002-08-27 00:00:00 | Bovine and Sprague-Dawley rats; mammalian / Pulmonary, cardiac and expressed in Baculovirus infected Sf21(Spodoptera frugiperda) insect cells | Cytosol | Quantitative match to experiments, Qualitative / Exact GENESIS implementation |
35 | MAPK-bistability -fig1c | Bhalla US et al. Science (2002) 297(5583):1018-23 ( peer-reviewed publication ). / 2002-11-07 00:00:00 | Generic mammalian / NIH 3T3 Expression | Surface - Nucleus | Quantitative match to experiments, Qualitative / Exact GENESIS implementation |
36 | luciferase | L. Yu. Brovko et al 1994, Biochemistry (Moscow) 59(2):195-201, 1994 ( peer-reviewed publication ). / 2002-12-12 00:00:00 | E. Coli / - | Cytosol | Qualitative / Approximate implementation |
37 | SERCA | Mahaney JE. et al. Biophys J. (2000) 78(3) 1306-23. ( peer-reviewed publication ) / 2002-12-31 00:00:00 | Canine / Cardiac; expressed in Baculovirus infected Sf21(Spodoptera frugiperda) insect cells. | Microsomes | Quantitative match to experiments, Qualitative / Exact GENESIS implementation |
42 | CDK2-CyclinA_ activation_ pathway | Morris MC. et al. J Biol Chem. (2002) 277(26):23847-53. ( peer-reviewed publication ) / 2003-01-11 00:00:00 | Human, Xenopus / Expressed in E.coli | Cytosol | Qualitative / Exact GENESIS implementation |
43 | CDK2-CyclinA_ activation_ improved | Morris MC. et al. J Biol Chem. (2002) 277(26):23847-53. ( peer-reviewed publication ) / 2003-01-11 00:00:00 | Human, Xenopus / Expressed in E.coli | Cytosol | Quantitative match to experiments / Exact GENESIS implementation |
44 | MAPK_Asthagiri_ no_fb | Asthagiri AR and Lauffenburger DA. Biotechnol Prog. (2001) 17(2):227-39. ( peer-reviewed publication ). / 2003-02-22 00:00:00 | Chinese hamster (Cricetulus griseus); mammalian / Ovary - CHO cell line | Surface, cytosol | Quantitative match to experiments, Qualitative / Mathematically equivalent |
45 | MAPK_Asthagiri_ adapt_fb | Asthagiri AR and Lauffenburger DA. Biotechnol Prog. (2001) 17(2):227-39. ( peer-reviewed publication ). / 2003-02-22 00:00:00 | Chinese hamster (Cricetulus griseus); mammalian / Ovary - CHO cell line | Surface, cytosol | Quantitative match to experiments, Qualitative / Mathematically equivalent |
46 | MAPK_Asthagiri_ enz_fb | Asthagiri AR and Lauffenburger DA. Biotechnol Prog. (2001) 17(2):227-39. ( peer-reviewed publication ). / 2003-02-22 00:00:00 | Chinese hamster (Cricetulus griseus); mammalian / Ovary - CHO cell line | Surface + cytosol | Qualitative / Approximate implementation |
47 | PKA_2003 | Bhalla US. (2004) Biophys J. 87(2):733-44. ( peer-reviewed publication ) / 2003-04-28 00:00:00 | Generic mammalian / Generic | Cytosol + Cell membrane | Qualitative / Exact GENESIS implementation |
48 | PKC_2003 | Bhalla US. (2004) Biophys J. 87(2):733-44 .( peer-reviewed publication ) / 2003-04-28 00:00:00 | Generic mammalian / Generic | Cytosol + Cell membrane | Qualitative / Exact GENESIS implementation |
49 | CaMKII_2003 | Bhalla US. Biophys J. 2004 Aug;87(2):733-44. ( peer-reviewed publication ). / 2003-04-28 00:00:00 | Generic mammalian / Brain - Neuronal | Synapse | Qualitative / Exact GENESIS implementation |
50 | MAPK_network_ 2003 | Bhalla US Biophys J. 2004 Aug;87(2):745-53. ( peer-reviewed publication ) / 2003-04-28 00:00:00 | Generic mammalian / Brain - Neuronal | Synapse | Qualitative / Exact GENESIS implementation |
52 | EGFR_Signaling_ pathway | Quantification of Short Term Signaling by the EGFR Kholodenko et al, The J Biol Chem. , Vol 274, No. 42, Issue of October 15, pp. 30169 - 30181, 1999. ( peer-reviewed publication ) / 2003-05-17 00:00:00 | Harlan Sprague Dawley rat; mammalian / Hepatocytes | Cell membrane + cytosol | Qualitative / Mathematically equivalent |
55 | Chemotaxis | Bray et al. Mol.Biol.Cell (1993) 4(5): 469-482. ( peer-reviewed publication ) / 2003-06-10 00:00:00 | E. Coli / - | Cell membrane + cytosol | Quantitative match to experiments / Mathematically equivalent |