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Accession Type:
Network
Osc_Ca_
IP3metabolism
MIPP
CaMKII
CaM
PKC
IP3-3K
Gq
PLCbeta
134_dephos
145_dephos
IP4-system
IHP-system
1345_dephos
 Molecule
 Enzyme
 Reaction
CaRegulation
Othmer-Tang-mode
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Reaction List for pathway 1345_dephos (Pathway Number 131)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 134-inhib-3pase1
(uM^-1 s^-1)		2
(s^-1)		Kd(bf) = 2(uM)-1345_3pase
IP3(134)
  • IP3(134)-3pase-c
    mplx
    •   from Hoer et al, Biochem J 270; 1990
    2 145-inhib-3pase1
    (uM^-1 s^-1)    		1.75
    (s^-1)    		Kd(bf) = 1.75(uM)-1345_3pase
    IP3(145)
  • IP3(145)-3pase-c
    mplx
    •   from Hoer et al, Biochem J 270; 1990
    3 IP4-inhib-3pase1
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 0.5(uM)-IP4(3456)
    1345_3pase
    		IP4-3pase-cmplx
      from Hoer et al, Biochem J 270; 1990
    4 IP5-inhib-3pase1
    (uM^-1 s^-1)    		0.06
    (s^-1)    		Kd(bf) = 0.06(uM)-1345_3pase
    IP5(13456)
    		IP5-3pase-cmplx
      from Hoer and Oberdisse, Biochem J 278; 1991: 219-224
    5 IP6-inhib-3pase1
    (uM^-1 s^-1)    		0.003
    (s^-1)    		Kd(bf) = 0.003(uM)-1345_3pase
    IP6
  • IP6-inhib-3pase-
    cmplx
    •   from Hoer and Oberdisse, Biochem J 278; 1991: 219-224


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