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Result: 21 - 25 of 25 rows are displayed Previous of 2  Next

Molecule List for pathway CaMKII (Pathway Number 235) in Accession AMPAR_traff_model0 (Accession Number 59)

Default ordering is done according to Pathway Number. Table headers can be used for changing the default ordering.
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The entries are grouped according to Pathway Number and are alternately color coded using  and  color.
  NameAccession
Type
Initial
Conc.

(uM)
Volume
(fL)
BufferedSum Total Of
21 tot_CaMKII_PSDNetwork20No actCaMKII-PSD
 CaMKII-PSD
  •  CaMKII-thr305-PS
    D

  • 22 actCaMKII-PSDNetwork20No
  •  CaMKII-thr286-Ca
    M-PSD

     CaMKII-CaM-PSD
     tot-auto-PSD
  • 23 CaMKIINetwork200No
        Huge conc of CaMKII. In PSD it is 20-40% of protein, so we assume it is around 2.5% of protein in spine as a whole. This level is so high it is unlikely to matter much if we are off a bit. This comes to about 70 uM.
    24 tot_CaMKII_cytNetwork220No CaMKII-CaM
  •  CaMKII-thr286*-C
    aM

     CaMKII-thr286
     CaMKII***
     CaMK-thr305
     CaMKII
  •  basal_CaMKII_
    cyt

  • 25 NMDARNetwork1200No
        The stochiometry is a bit off here. Each NMDAR actually binds to a holoenzyme, about 12 CaMKII subunits. But our CaMKII calculations are in terms of individual subunits. So as a hack, we put in much more NMDAR than is actually there.

     
    Result: 21 - 25 of 25 rows are displayed Previous of 2  Next



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