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Molecule List for Accession AMPAR_CaMKII_weak_coupling (Accession Number65)

Default ordering is done according to Pathway Number. Table headers can be used for changing the default ordering.

arrow indicates that ordering is done according to ascending or descending order.
The entries are grouped according to Pathway Number and are alternately color coded using

and

color.

	Name	Pathway Name / Pathway No.	Accession Type	Initial Conc. (uM)	Volume (fL)	Buffered	Sum Total Of
1	CaMKII-thr305-PS D	CaMKII_PSD Pathway No. 292	Network	0	0.01	No	-
2	CaMKII***-PSD	CaMKII_PSD Pathway No. 292	Network	0	0.01	No	-
3	CaMKII-PSD	CaMKII_PSD Pathway No. 292	Network	0	0.01	No	-
4	CaMKII-thr286-PS D	CaMKII_PSD Pathway No. 292	Network	0	0.01	No	-
5	CaMKII-CaM-PSD	CaMKII_PSD Pathway No. 292	Network	0	0.01	No	-
6	CaMKII-thr286-Ca M-PSD	CaMKII_PSD Pathway No. 292	Network	0	0.01	No	-
7	basal_CaMKII_ PSD	CaMKII_PSD Pathway No. 292	Network	2	0.01	No	-
8	NMDAR	CaMKII_PSD Pathway No. 292	Network	120	0.01	No	-
	The stochiometry is a bit off here. Each NMDAR actually binds to a holoenzyme, about 12 CaMKII subunits. But our CaMKII calculations are in terms of individual subunits. So as a hack, we put in much more NMDAR than is actually there.
9	basal_CaMKII_ PSD_control	CaMKII_PSD Pathway No. 292	Network	2	0.01	Yes	-
10	tot-CaM-CaMKII-P SD	CaMKII_PSD Pathway No. 292	Network	0	0.01	No	CaMKII-thr286-Ca M-PSD CaMKII-CaM-PSD
11	tot-auto-PSD	CaMKII_PSD Pathway No. 292	Network	2	0.01	No	CaMKII-thr286-PS D CaMKII***-PSD basal_CaMKII_ PSD
12	tot_CaMKII_PSD	CaMKII_PSD Pathway No. 292	Network	2	0.01	No	actCaMKII-PSD CaMKII-PSD CaMKII-thr305-PS D
13	actCaMKII-PSD	CaMKII_PSD Pathway No. 292	Network	2	0.01	No	CaMKII-thr286-Ca M-PSD CaMKII-CaM-PSD tot-auto-PSD
14	286P-PSD	CaMKII_PSD Pathway No. 292	Network	0	0.01	No	CaMKII-thr286-Ca M-PSD CaMKII-thr286-PS D
15	PP1-active_ CaMKII_PSD	PP1_CaMKII_PSD Pathway No. 291	Network	2	0.01	No	-
	Cohen et al Meth Enz 159 390-408 is main source of info conc = 1.8 uM in their study, here it is almost the same. In this model of weak coupling between CaMKII and AMPAR, this phosphatase pool acts only on the CaMKII present in the PSD.
16	A_B	AMPAR_memb Pathway No. 290	Network	0	0.01	No	-
17	A831*_B	AMPAR_memb Pathway No. 290	Network	0	0.01	No	-
18	A_B831*	AMPAR_memb Pathway No. 290	Network	0	0.01	No	-
19	A831_B831	AMPAR_memb Pathway No. 290	Network	0	0.01	No	-
20	A845*_B	AMPAR_memb Pathway No. 290	Network	0	0.01	No	-

Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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