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Molecule List for Accession CaMKII (Accession Number33)

Default ordering is done according to Pathway Number. Table headers can be used for changing the default ordering.

arrow indicates that ordering is done according to ascending or descending order.
The entries are grouped according to Pathway Number and are alternately color coded using

and

color.

	Name	Pathway Name / Pathway No.	Accession Type	Initial Conc. (uM)	Volume (fL)	Buffered	Sum Total Of
1	Ca	Shared_Object_ CaMKII Pathway No. 172	Network	0.07	0.1309	No	-
	70 nM initial conc from Holmes.
2	CaN	CaN Pathway No. 175	Network	3.6415	0.1309	No	-
	Holmes assumes that there are 286 calcinuerin molecules.
3	CaN-CaM	CaN Pathway No. 175	Network	0	0.1309	No	-
4	CaN-CaMCa	CaN Pathway No. 175	Network	0	0.1309	No	-
5	CaN-CaMCa2	CaN Pathway No. 175	Network	0	0.1309	No	-
6	CaN-CaMCa3	CaN Pathway No. 175	Network	0	0.1309	No	-
7	CaN-CaMCa4	CaN Pathway No. 175	Network	0	0.1309	No	-
8	CAMKII-CaMCa	CaMKII Pathway No. 174	Network	0	0.1309	No	-
9	CaMKII-CaMCa2	CaMKII Pathway No. 174	Network	0	0.1309	No	-
10	CaMKII	CaMKII Pathway No. 174	Network	12.7325	0.1309	No	-
	Init level is 100 holoenzymes of 10 subunits each.
11	CaMKII-CaMCa3	CaMKII Pathway No. 174	Network	0	0.1309	No	-
12	CaMKII-CaMCa4	CaMKII Pathway No. 174	Network	0	0.1309	No	-
13	CaMKII-CaM	CaMKII Pathway No. 174	Network	0	0.1309	No	-
14	Trapped-T286	CaMKII Pathway No. 174	Network	0	0.1309	No	-
15	Total_CaMKII	CaMKII Pathway No. 174	Network	127.325	0.1309	No	-
	This is not directly in the Holmes model. It is a trick used in GENESIS/Kinetikit to scale activity down for intramolecular reactions. Here it is used to scale the autophosph reactions such that only neighboring subunits will phosphorylate each other. This is done by scaling down the actual conc (in the enzyme parent, Tot-active-CaMKII) by the total conc such that instead of a conc, we the fraction of nearby subunits that will be active. Note that this conc of 10000 CaMKII subunits is 10 times the true conc, since only 1/10 of the molecules are neighboring molecules.
16	Capped	CaMKII Pathway No. 174	Network	0	0.1309	No	-
17	Autonomous	CaMKII Pathway No. 174	Network	0	0.1309	No	-
18	Tot-active-CaMKI I	CaMKII Pathway No. 174	Network	0	0.1309	No	CaMKII-CaMCa4 Trapped-T286 Capped Autonomous
19	CaM	CaM Pathway No. 173	Network	79.9997	0.1309	No	-
	Init conc form model is 80 uM.
20	CaMCa	CaM Pathway No. 173	Network	0	0.1309	No	-

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