NCBS Home page
Accession List
Pathway List
Search
Authorized Users
Help
News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By


 
Result: 1 - 9 of 9 rows are displayed

Reaction List for pathway Gq (Pathway Number 5) in Accession fig2_egfr (Accession Number 1)

Entries are grouped according to Pathway Number and they are alternately color coded using  and  color.
Further ordering can be done to the table header.  indicates that ordering is done according to ascending or descending order.
Keq is calculated only for first order reactions.
Kd is calculated only for second order reactions. [nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules]
  Reaction
Name
Pathway Name / 
Pathway No.
KfKbKdtauReagents
1 
  • RecLigandBinding
  • Gq

    Pathway No. 5
    16.8
    (uM^-1 s^-1)
    10
    (s^-1)
    Kd(bf) = 0.5952(uM)-  Substrate:
     mGluR
     Glu

     Products:
     Rec-Glu
    2 Basal-Act-GGq

    Pathway No. 5
    0.0001
    (s^-1)
    0
    (uM^-1 s^-1)
    --  Substrate:
     G-GDP

     Products:
     G*GTP
     BetaGamma
    3 Trimerize-GGq

    Pathway No. 5
    6
    (uM^-1 s^-1)
    0
    (s^-1)
    --  Substrate:
     G*GDP
     BetaGamma

     Products:
     G-GDP
    4 Inact-GGq

    Pathway No. 5
    0.0133
    (s^-1)
    0
    (s^-1)
    --  Substrate:
     G*GTP

     Products:
     G*GDP
    5 Rec-Glu-bind-GqGq

    Pathway No. 5
    0.006
    (uM^-1 s^-1)
    0.0001
    (s^-1)
    Kd(bf) = 0.0167(uM)-  Substrate:
     G-GDP
     Rec-Glu

     Products:
     Rec-Glu-Gq
    6 Glu-bind-Rec-GqGq

    Pathway No. 5
    16.8
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.006(uM)-  Substrate:
     Glu
     Rec-Gq

     Products:
     Rec-Glu-Gq
    7 Activate-GqGq

    Pathway No. 5
    0.01
    (s^-1)
    0
    (uM^-2 s^-1)
    --  Substrate:
     Rec-Glu-Gq

     Products:
     G*GTP
     BetaGamma
     Rec-Glu
    8 Rec-bind-GqGq

    Pathway No. 5
    0.6
    (uM^-1 s^-1)
    1
    (s^-1)
    Kd(bf) = 1.6667(uM)-  Substrate:
     G-GDP
     mGluR

     Products:
     Rec-Gq
    9 
  • Antag-bind-Rec-G
    q
  • Gq

    Pathway No. 5
    60
    (uM^-1 s^-1)
    0.01
    (s^-1)
    Kd(bf) = 0.0002(uM)-  Substrate:
     Rec-Gq
     mGluRAntag

     Products:
     Blocked-rec-Gq

     
    Result: 1 - 9 of 9 rows are displayed



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.