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Accession Type:
Network
fig2_egfr
Shared_Object_
fig2_egfr
PKC
PLA2
PLCbeta
Gq
MAPK
Ras
EGFR
 Molecule
 Enzyme
 Reaction
Sos
PLC_g
CaRegulation

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Reaction List for pathway EGFR (Pathway Number 8)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.
  Name KfKbKdtauSubstrateProduct
1 act_EGFRkf
(uM^-1 s^-1)
0.25
(s^-1)
Kd(bf) = 0.0595(uM)-EGFR
EGF
L.EGFR
2 dephosph_Shckf
(s^-1)
0
(s^-1)
--SHC*
SHC
3 Internalizekf
(s^-1)
0.0003
(s^-1)
Keq = 0.165(uM)434.783secL.EGFR
Internal_L.EGFR


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