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Molecule Parameter List for MAPK-tyr | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by  color. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| MAPK-tyr participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 0 | 0 | 2 | 2 | 0 | 0 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
| fig2_egfr | 1 | Network | Shared_Object_fig2_egfr, PKC, PLA2, PLCbeta, Gq, MAPK, Ras, EGFR, Sos, PLC_g, CaRegulation |
| This network was used to generate figure 2 in Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It consists of the MAPK cascade in a feedback loop with PKC, and receives input from the EGFR in the synapse. Demonstration script files for generating the figures in the paper, including figure 2, are available here. | |||
MAPK-tyr acting as a Molecule in fig2_egfr Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | |
| MAPK-tyr | fig2_egfr Accession No. : 1 | MAPK Pathway No. : 6 | 0 | 1000 | No | |
MAPK-tyr acting as a Substrate for an Enzyme in fig2_egfr Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | |
| 1 | MAPKK* / MAPKKthr | fig2_egfr Accession No. : 1 | MAPK Pathway No. : 6 | 0.0462963 | 0.15 | 4 | explicit E-S complex | Substrate MAPK-tyr Product MAPK* |
| 2 | MKP-1 / MKP1-tyr-deph | fig2_egfr Accession No. : 1 | fig2_egfr Pathway No. : 1 | 0.0666667 | 1 | 4 | explicit E-S complex | Substrate MAPK-tyr Product MAPK |
MAPK-tyr acting as a Product of an Enzyme in fig2_egfr Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | |
| 1 | MAPKK* / MAPKKtyr | fig2_egfr Accession No. : 1 | MAPK Pathway No. : 6 | 0.0462963 | 0.15 | 4 | explicit E-S complex | Substrate MAPK Product MAPK-tyr |
| 2 | MKP-1 / MKP1-thr-deph | fig2_egfr Accession No. : 1 | fig2_egfr Pathway No. : 1 | 0.0666667 | 1 | 4 | explicit E-S complex | Substrate MAPK* Product MAPK-tyr |