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Molecule Parameter List for A845_B831

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

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Statistics

A845_B831 participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	2	3	0	7	7	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
AMPAR_CaMKII_ weak_coupling	65	Network	Shared_Object_AMPAR_CaMKII_weak_coupling, CaMKII, CaM, PP1, PP2B, PP1_PSD, AMPAR, PKA, AC, AMPAR_memb, PP1_CaMKII_PSD, CaMKII_PSD
This is a model of weak coupling between the AMPAR traffikcing bistability, and the CaMKII autophosphorylation bistability. In this model, there are three stable states: Both off, AMPAR on, or both on. The fourth possible state: CaMKII on but AMPAR off, is not truly stable, since over the course of hours the AMPAR also turns on.

A845*_B831* acting as a Molecule in AMPAR_CaMKII_weak_coupling Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
A845_B831	AMPAR_CaMKII_ weak_coupling Accession No. : 65	AMPAR Pathway No. : 287	0	0.09	No

A845_B831	AMPAR_CaMKII_ weak_coupling Accession No. : 65	AMPAR_memb Pathway No. : 290	0	0.01	No

A845*_B831* acting as a Summed Molecule in AMPAR_CaMKII_weak_coupling Network

	Accession Nane	Pathway Name	Target	Input
1	AMPAR_CaMKII_ weak_coupling Accession No. : 65	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. : 281	I_845-P	A831845_B831* A845_B831 A831845_B A845_B A831_B831845 A_B831845 A831_B845 A_B845*
2	AMPAR_CaMKII_ weak_coupling Accession No. : 65	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. : 281	Ser845-P	A845_B A831845_B A845_B831* A831845_B831* A_B845* A831_B845 A_B831845 A831_B831845*
3	AMPAR_CaMKII_ weak_coupling Accession No. : 65	Shared_Object_ AMPAR_CaMKII_ weak_coupling Pathway No. : 281	Ser831-P	A831845_B845* A845_B831845* A831_B845 A_B831845 A831845_B A845_B831 A831_B A_B831

A845*_B831* acting as a Substrate for an Enzyme in AMPAR_CaMKII_weak_coupling Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	CaM_Ca_n-CaNAB / PP2B[19]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	PP2B Pathway No. : 285	4.97061	2	4	explicit E-S complex	Substrate A845_B831 Product A_B831*
2	CaM_Ca_n-CaNAB / PP2B[11]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	PP2B Pathway No. : 285	4.97061	2	4	explicit E-S complex	Substrate A845_B831 Product A_B831*
3	PKA-active / PKA[30]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	PKA Pathway No. : 288	7.50021	6	4	explicit E-S complex	Substrate A845_B831 Product A845_B831845*
4	PKA-active / PKA[9]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	PKA Pathway No. : 288	7.50021	6	4	explicit E-S complex	Substrate A845_B831 Product A845_B831845*
5	PP1-active_PSD / PP1[15]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	PP1_PSD Pathway No. : 286	0.971451	0.17	4	explicit E-S complex	Substrate A845_B831 Product A_B831*
6	PP1-active_PSD / PP1[22]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	PP1_PSD Pathway No. : 286	2.00005	0.35	4	explicit E-S complex	Substrate A845_B831 Product A845*_B
7	actCaMKII-PSD / CaMKII[10]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A845_B831 Product A831845_B831*

A845*_B831* acting as a Product of an Enzyme in AMPAR_CaMKII_weak_coupling Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	CaM_Ca_n-CaNAB / PP2B[31]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	PP2B Pathway No. : 285	4.97061	2	4	explicit E-S complex	Substrate A845_B831845* Product A845_B831
2	CaM_Ca_n-CaNAB / PP2B[9]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	PP2B Pathway No. : 285	4.97061	2	4	explicit E-S complex	Substrate A845_B831845* Product A845_B831
3	PKA-active / PKA[18]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	PKA Pathway No. : 288	7.50021	6	4	explicit E-S complex	Substrate A_B831* Product A845_B831
4	PKA-active / PKA[11]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	PKA Pathway No. : 288	7.50021	6	4	explicit E-S complex	Substrate A_B831* Product A845_B831
5	PP1-active_PSD / PP1[13]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	PP1_PSD Pathway No. : 286	0.971451	0.17	4	explicit E-S complex	Substrate A845_B831845* Product A845_B831
6	PP1-active_PSD / PP1[26]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	PP1_PSD Pathway No. : 286	2.00005	0.35	4	explicit E-S complex	Substrate A831845_B831* Product A845_B831
7	actCaMKII-PSD / CaMKII[6]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A845_B Product* A845_B831

Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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Molecule Parameter List for A845*_B831*

Molecule Parameter List for A845_B831