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Molecule Parameter List for tot-auto-PSD | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Statistics | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| tot-auto-PSD participated as | Molecule | Sum total of | Enzyme | Substrate of an enzyme | Product of an enzyme | Substrate in Reaction | Product in Reaction |
| No. of occurrences | 1 | 2 | 3 | 0 | 0 | 0 | 0 |
Accession and Pathway Details |
| Accession Name | Accession No. | Accession Type | Pathway Link |
weak_coupling | 65 | Network | Shared_Object_AMPAR_CaMKII_weak_coupling, CaMKII, CaM, PP1, PP2B, PP1_PSD, AMPAR, PKA, AC, AMPAR_memb, PP1_CaMKII_PSD, CaMKII_PSD |
| This is a model of weak coupling between the AMPAR traffikcing bistability, and the CaMKII autophosphorylation bistability. In this model, there are three stable states: Both off, AMPAR on, or both on. The fourth possible state: CaMKII on but AMPAR off, is not truly stable, since over the course of hours the AMPAR also turns on. | |||
tot-auto-PSD acting as a Molecule in AMPAR_CaMKII_weak_coupling Network
| Name | Accession Name | Pathway Name | Initial Conc. (uM) | Volume (fL) | Buffered | |
| tot-auto-PSD | weak_coupling Accession No. : 65 | CaMKII_PSD Pathway No. : 292 | 2 | 0.01 | No | |
tot-auto-PSD acting as a Summed Molecule in AMPAR_CaMKII_weak_coupling Network
| Accession Nane | Pathway Name | Target | Input | |
| 1 | weak_coupling Accession No. : 65 | CaMKII_PSD Pathway No. : 292 | tot-auto-PSD | D CaMKII***-PSD PSD |
| 2 | weak_coupling Accession No. : 65 | CaMKII_PSD Pathway No. : 292 | actCaMKII-PSD | M-PSD CaMKII-CaM-PSD tot-auto-PSD |
tot-auto-PSD acting as an Enzyme in AMPAR_CaMKII_weak_coupling Network
| Enzyme Molecule / Enzyme Activity | Accession Name | Pathway Name | Km (uM) | kcat (s^-1) | Ratio | Enzyme Type | Reagents | |
| 1 | tot-auto-PSD / auton-305-PSD | weak_coupling Accession No. : 65 | CaMKII_PSD Pathway No. : 292 | 500 | 6 | 4 | explicit E-S complex | Substrate D Product CaMKII***-PSD |
| 2 | tot-auto-PSD / auton-286-PSD | weak_coupling Accession No. : 65 | CaMKII_PSD Pathway No. : 292 | 500.002 | 0.5 | 4 | explicit E-S complex | Substrate CaMKII-CaM-PSD Product M-PSD |
| 3 | tot-auto-PSD / auton-autoph | weak_coupling Accession No. : 65 | CaMKII_PSD Pathway No. : 292 | 500.005 | 2 | 4 | explicit E-S complex | Substrate CaMKII-PSD Product D |
color.