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Molecule Parameter List for PKC-Ca

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

*PKC-Ca* participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	25	0	0	0	0	99	49

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
Ajay_Bhalla_ 2007_ReacDiff3	84	Network	Shared_Object_Ajay_Bhalla_2007_ReacDiff3, PKC, PLA2, MAPK, PLA2, Ras, CaM, chain, kinetics, PKC, MAPK, Ras, CaM, kinetics[1], PKC, PLA2, MAPK, Ras, CaM, kinetics[2], PKC, PLA2, MAPK, Ras, CaM, kinetics[3], PKC, PLA2, MAPK, Ras, CaM, kinetics[4], PKC, PLA2, MAPK, Ras, CaM, kinetics[5], PKC, PLA2, MAPK, Ras, MAPK, CaM, kinetics[6], PKC, PLA2, MAPK, Ras, CaM, kinetics[7], PKC, PLA2, MAPK, Ras, CaM, PKC, kinetics[8], PLA2, MAPK, Ras, CaM, kinetics[9], PKC, PLA2, MAPK, Ras, CaM, kinetics[10], PKC, PLA2, MAPK, Ras, CaM, kinetics[11], PKC, PLA2, MAPK, Ras, CaM, kinetics[12], PKC, PLA2, Ras, CaM, kinetics[13], PKC, PLA2, MAPK, Ras, CaM, kinetics[14], PKC, PLA2, MAPK, Ras, CaM, kinetics[15], PKC, PLA2, MAPK, Ras, kinetics[16], CaM, PKC, PLA2, MAPK, Ras, CaM, kinetics[17], PKC, PLA2, MAPK, Ras, CaM, kinetics[18], PKC, PLA2, MAPK, Ras, CaM, kinetics[19], PKC, PLA2, MAPK, Ras, CaM, kinetics[20], PKC, PLA2, MAPK, Ras, CaM, kinetics[21], PKC, PLA2, MAPK, Ras, CaM, kinetics[22], PKC, PLA2, MAPK, Ras, CaM, kinetics[23], PKC, PLA2, MAPK, Ras, CaM
This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_bistable model. The original single-compartment model is repeated 25 times. In addition, a subset (33 out of 50) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. Here D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) so the kf and kb of this reaction for these 10 micron compartments are both 0.001/sec. The basal calcium level in this model is held at 95 nM which is rather close to threshold for the flip to the active state. This is necessary to sustain active propagation of activation. The stimulus file bis6-propgn_D1e-13_FigEF which was used for the model to replicate Figure 4E and 4F from the paper.

PKC-Ca acting as a Molecule in Ajay_Bhalla_2007_ReacDiff3 Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 919	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 927	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 932	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 938	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 944	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 950	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 956	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 963	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 969	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 974	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 981	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 987	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 993	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 999	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1004	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1010	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1016	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1022	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1028	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1034	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1040	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1046	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1052	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1058	0	125.7	No
PKC-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1064	0	125.7	No

PKC-Ca acting as a Substrate in a reaction in Ajay_Bhalla_2007_ReacDiff3 Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

	Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
1	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
2	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 919	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
3	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 919	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
4	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 919	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
5	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
6	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 927	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
7	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 927	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
8	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 927	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
9	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
10	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 932	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
11	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 932	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
12	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 932	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
13	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
14	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 938	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
15	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 938	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
16	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 938	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
17	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
18	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 944	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
19	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 944	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
20	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 944	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
21	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
22	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 950	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
23	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 950	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
24	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 950	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
25	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
26	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 956	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
27	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 956	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
28	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 956	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
29	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
30	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 963	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
31	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 963	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
32	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 963	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
33	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
34	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 969	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
35	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 969	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
36	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 969	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
37	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
38	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 974	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
39	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 974	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
40	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 974	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
41	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
42	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 981	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
43	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 981	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
44	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 981	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
45	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
46	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 987	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
47	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 987	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
48	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 987	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
49	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
50	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 993	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
51	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 993	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
52	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 993	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
53	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
54	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 999	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
55	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 999	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
56	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 999	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
57	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
58	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1004	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
59	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1004	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
60	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1004	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
61	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
62	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1010	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
63	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1010	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
64	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1010	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
65	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
66	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1016	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
67	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1016	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
68	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1016	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
69	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
70	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1022	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
71	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1022	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
72	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1022	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
73	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
74	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1028	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
75	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1028	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
76	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1028	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
77	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
78	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1034	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
79	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1034	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
80	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1034	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
81	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
82	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1040	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
83	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1040	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
84	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1040	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
85	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
86	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1046	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
87	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1046	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
88	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1046	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
89	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
90	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1052	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
91	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1052	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
92	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1052	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
93	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
94	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1058	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
95	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1058	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
96	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1058	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.
97	PKC-act-by-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1064	0.008 (uM^-1 s^-1)	8.6348 (s^-1)	Kd(bf) = 1079.4148(uM)	-	Substrate DAG PKC-Ca Product PKC-Ca-DAG
	Need est of rate. Assume it is fast Obtained from param search kf raised 10 X : see Shinomura et al PNAS 88 5149-5153 1991. kf changed from 3.865e-7 to 2.0e-7 in line with closer analysis of Shinomura data. 26 June 1996: Corrected DAG data: reduce kf 15x from 2e-7 to 1.333e-8
98	PKC-Ca-to-memb	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1064	1.2705 (s^-1)	3.5026 (s^-1)	Keq = 2.7569(uM)	0.21sec	Substrate PKC-Ca Product PKC-Ca-memb*
99	PKC-act-by-Ca-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1064	0.0012 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 83.3333(uM)	-	Substrate AA PKC-Ca Product PKC-Ca-AA*
	Schaechter and Benowitz We have to increase Kf for conc scaling Changed kf to 2e-9 on Sept 19, 94. This gives better match.

PKC-Ca acting as a Product in a reaction in Ajay_Bhalla_2007_ReacDiff3 Network

	Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
1	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
2	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 919	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
3	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
4	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 927	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
5	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
6	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 932	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
7	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
8	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 938	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
9	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
10	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 944	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
11	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
12	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 950	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
13	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
14	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 956	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
15	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
16	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 963	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
17	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
18	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 969	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
19	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
20	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 974	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
21	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
22	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 981	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
23	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
24	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 987	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
25	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
26	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 993	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
27	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
28	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 999	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
29	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
30	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1004	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
31	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
32	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1010	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
33	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
34	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1016	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
35	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
36	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1022	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
37	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
38	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1028	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
39	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
40	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1034	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
41	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
42	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1040	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
43	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
44	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1046	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
45	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
46	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1052	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
47	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-Ca Product PKC-Ca
48	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1058	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
49	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1064	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5

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