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Molecule Parameter List for PKC-cytosolic

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by

color.

Statistics

*PKC-cytosolic* participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	25	0	0	0	0	124	24

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
Ajay_Bhalla_ 2007_ReacDiff3	84	Network	Shared_Object_Ajay_Bhalla_2007_ReacDiff3, PKC, PLA2, MAPK, PLA2, Ras, CaM, chain, kinetics, PKC, MAPK, Ras, CaM, kinetics[1], PKC, PLA2, MAPK, Ras, CaM, kinetics[2], PKC, PLA2, MAPK, Ras, CaM, kinetics[3], PKC, PLA2, MAPK, Ras, CaM, kinetics[4], PKC, PLA2, MAPK, Ras, CaM, kinetics[5], PKC, PLA2, MAPK, Ras, MAPK, CaM, kinetics[6], PKC, PLA2, MAPK, Ras, CaM, kinetics[7], PKC, PLA2, MAPK, Ras, CaM, PKC, kinetics[8], PLA2, MAPK, Ras, CaM, kinetics[9], PKC, PLA2, MAPK, Ras, CaM, kinetics[10], PKC, PLA2, MAPK, Ras, CaM, kinetics[11], PKC, PLA2, MAPK, Ras, CaM, kinetics[12], PKC, PLA2, Ras, CaM, kinetics[13], PKC, PLA2, MAPK, Ras, CaM, kinetics[14], PKC, PLA2, MAPK, Ras, CaM, kinetics[15], PKC, PLA2, MAPK, Ras, kinetics[16], CaM, PKC, PLA2, MAPK, Ras, CaM, kinetics[17], PKC, PLA2, MAPK, Ras, CaM, kinetics[18], PKC, PLA2, MAPK, Ras, CaM, kinetics[19], PKC, PLA2, MAPK, Ras, CaM, kinetics[20], PKC, PLA2, MAPK, Ras, CaM, kinetics[21], PKC, PLA2, MAPK, Ras, CaM, kinetics[22], PKC, PLA2, MAPK, Ras, CaM, kinetics[23], PKC, PLA2, MAPK, Ras, CaM
This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_bistable model. The original single-compartment model is repeated 25 times. In addition, a subset (33 out of 50) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. Here D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) so the kf and kb of this reaction for these 10 micron compartments are both 0.001/sec. The basal calcium level in this model is held at 95 nM which is rather close to threshold for the flip to the active state. This is necessary to sustain active propagation of activation. The stimulus file bis6-propgn_D1e-13_FigEF which was used for the model to replicate Figure 4E and 4F from the paper.

PKC-cytosolic acting as a Molecule in Ajay_Bhalla_2007_ReacDiff3 Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 919	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 927	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 932	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 938	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 944	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 950	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 956	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 963	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 969	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 974	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 981	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 987	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 993	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 999	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1004	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1010	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1016	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1022	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1028	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1034	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1040	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1046	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1052	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1058	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen
PKC-cytosolic	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1064	1	125.7	No
Marquez et al J. Immun 149,2560(92) est 1e6/cell for chromaffin cells We will use 1 uM as our initial concen

PKC-cytosolic acting as a Substrate in a reaction in Ajay_Bhalla_2007_ReacDiff3 Network

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.

	Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
1	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 919	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
2	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 919	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
3	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 919	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
4	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 919	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
5	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
6	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 927	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
7	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 927	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
8	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 927	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
9	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 927	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
10	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
11	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 932	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
12	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 932	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
13	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 932	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
14	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 932	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
15	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
16	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 938	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
17	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 938	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
18	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 938	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
19	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 938	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
20	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
21	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 944	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
22	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 944	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
23	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 944	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
24	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 944	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
25	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
26	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 950	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
27	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 950	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
28	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 950	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
29	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 950	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
30	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
31	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 956	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
32	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 956	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
33	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 956	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
34	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 956	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
35	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
36	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 963	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
37	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 963	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
38	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 963	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
39	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 963	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
40	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
41	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 969	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
42	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 969	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
43	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 969	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
44	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 969	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
45	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
46	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 974	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
47	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 974	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
48	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 974	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
49	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 974	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
50	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
51	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 981	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
52	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 981	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
53	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 981	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
54	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 981	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
55	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
56	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 987	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
57	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 987	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
58	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 987	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
59	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 987	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
60	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
61	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 993	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
62	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 993	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
63	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 993	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
64	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 993	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
65	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
66	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 999	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
67	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 999	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
68	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 999	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
69	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 999	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
70	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
71	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1004	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
72	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1004	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
73	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1004	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
74	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1004	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
75	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
76	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1010	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
77	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1010	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
78	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1010	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
79	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1010	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
80	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
81	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1016	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
82	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1016	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
83	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1016	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
84	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1016	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
85	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
86	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1022	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
87	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1022	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
88	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1022	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
89	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1022	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
90	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
91	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1028	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
92	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1028	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
93	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1028	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
94	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1028	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
95	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
96	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1034	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
97	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1034	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
98	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1034	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
99	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1034	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
100	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
101	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1040	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
102	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1040	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
103	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1040	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
104	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1040	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
105	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
106	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1046	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
107	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1046	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
108	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1046	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
109	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1046	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
110	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
111	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1052	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
112	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1052	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
113	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1052	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
114	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1052	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
115	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
116	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1058	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
117	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1058	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
118	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1058	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
119	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1058	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9
120	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
121	PKC-act-by-Ca	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1064	0.6 (uM^-1 s^-1)	0.5 (s^-1)	Kd(bf) = 0.8333(uM)	-	Substrate Ca PKC-cytosolic Product PKC-Ca
	Need est of rate of assoc of Ca and PKC. Assume it is fast The original parameter-searched kf of 439.4 has been scaled by 1/6e8 to account for change of units to n. Kf now 8.16e-7, kb=.6085 Raised kf to 1e-6 to match Ca curve, kb to .5
122	PKC-basal-act	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1064	1 (s^-1)	50 (s^-1)	Keq = 50(uM)	0.02sec	Substrate PKC-cytosolic Product PKC-basal*
	Initial basal levels were set by kf = 1, kb = 20. In model, though, the basal levels of PKC activity are higher.
123	PKC-act-by-AA	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1064	0.0001 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 833.3333(uM)	-	Substrate AA PKC-cytosolic Product PKC-AA*
	Raise kf from 1.667e-10 to 2e-10 to get better match to data.
124	PKC-n-DAG	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	PKC Pathway No. : 1064	0.0006 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 166.6664(uM)	-	Substrate DAG PKC-cytosolic Product PKC-DAG
	kf raised 10 X based on Shinomura et al PNAS 88 5149-5153 1991 closer analysis of Shinomura et al: kf now 1e-8 (was 1.66e-8). Further tweak. To get sufficient AA synergy, increase kf to 1.5e-8 26 June 1996: Corrected DAG levels: reduce kf by 15x from 1.5e-8 to 1e-9

PKC-cytosolic acting as a Product in a reaction in Ajay_Bhalla_2007_ReacDiff3 Network

	Name	Accession Name	Pathway Name	Kf	Kb	Kd	tau	Reagents
1	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
2	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
3	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
4	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
5	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
6	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
7	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
8	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
9	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
10	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
11	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
12	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
13	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
14	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
15	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
16	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
17	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
18	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
19	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
20	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
21	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
22	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
23	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic
24	diff	Ajay_Bhalla_ 2007_ReacDiff3 Accession No. : 84	Shared_Object_ Ajay_Bhalla_ 2007_ReacDiff3 Pathway No. : 918	0.001 (s^-1)	0.001 (s^-1)	Keq = 1(uM)	500sec	Substrate PKC-cytosolic Product PKC-cytosolic

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