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Molecule Parameter List for PLA2-cytosolic

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
PLA2-cytosolic participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences25002507449

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • Ajay_Bhalla_
    2007_ReacDiff3
    		• 84NetworkShared_Object_Ajay_Bhalla_2007_ReacDiff3,  PKC,  PLA2,  
    MAPK,  PLA2,  Ras,  CaM,  chain,  kinetics,  PKC,  MAPK,  Ras,  CaM,  kinetics[1],  
    PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[2],  PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[3],  
    PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[4],  PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[5],  
    PKC,  PLA2,  MAPK,  Ras,  MAPK,  CaM,  kinetics[6],  PKC,  PLA2,  MAPK,  Ras,  
    CaM,  kinetics[7],  PKC,  PLA2,  MAPK,  Ras,  CaM,  PKC,  kinetics[8],  PLA2,  
    MAPK,  Ras,  CaM,  kinetics[9],  PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[10],  
    PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[11],  PKC,  PLA2,  MAPK,  Ras,  CaM,  
    kinetics[12],  PKC,  PLA2,  Ras,  CaM,  kinetics[13],  PKC,  PLA2,  MAPK,  
    Ras,  CaM,  kinetics[14],  PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[15],  
    PKC,  PLA2,  MAPK,  Ras,  kinetics[16],  CaM,  PKC,  PLA2,  MAPK,  Ras,  CaM,  
    kinetics[17],  PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[18],  PKC,  PLA2,  
    MAPK,  Ras,  CaM,  kinetics[19],  PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[20],  
    PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[21],  PKC,  PLA2,  MAPK,  Ras,  CaM,  
    kinetics[22],  PKC,  PLA2,  MAPK,  Ras,  CaM,  kinetics[23],  PKC,  PLA2,  
    MAPK,  Ras,  CaM 
    This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_bistable model. The original single-compartment model is repeated 25 times.
    In addition, a subset (33 out of 50) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. Here D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) so the kf and kb of this reaction for these 10 micron compartments are both 0.001/sec.
    The basal calcium level in this model is held at 95 nM which is rather close to threshold for the flip to the active state. This is necessary to sustain active propagation of activation.
    The stimulus file bis6-propgn_D1e-13_FigEF which was used for the model to replicate Figure 4E and 4F from the paper.

    PLA2-cytosolic acting as a Molecule in      Ajay_Bhalla_2007_ReacDiff3 Network
    NameAccession NamePathway NameInitial Conc.
    (uM)    		Volume
    (fL)    		Buffered
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 920    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 922    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 933    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 939    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 945    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 951    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 957    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 964    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 970    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 976    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 982    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 988    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 994    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1000    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1005    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1011    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1017    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1023    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1029    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1035    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1041    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1047    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1053    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1059    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM
    PLA2-cytosolic
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1065    		0.4125.7No
    Calculated cytosolic was 20 nm from Wijkander and Sundler However, Leslie and Channon use about 400 nM. Need to confirm, but this is the value I use here. Another recalc of W&S gives 1uM

    PLA2-cytosolic acting as a Substrate for an Enzyme in      Ajay_Bhalla_2007_ReacDiff3 Network
     Enzyme Molecule /
    Enzyme Activity    		Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    2MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics
    Pathway No. : 926    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    3MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[1]
    Pathway No. : 931    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    4MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[2]
    Pathway No. : 937    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    5MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[3]
    Pathway No. : 943    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    6MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[4]
    Pathway No. : 949    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    7MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[5]
    Pathway No. : 955    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    8MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[6]
    Pathway No. : 962    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    9MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[7]
    Pathway No. : 968    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    10MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[8]
    Pathway No. : 975    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    11MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[9]
    Pathway No. : 980    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    12MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[10]
    Pathway No. : 986    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    13MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[11]
    Pathway No. : 992    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    14MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[12]
    Pathway No. : 998    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    15MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[13]
    Pathway No. : 1003    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    16MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[14]
    Pathway No. : 1009    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    17MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[15]
    Pathway No. : 1015    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    18MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[16]
    Pathway No. : 1020    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    19MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[17]
    Pathway No. : 1027    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    20MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[18]
    Pathway No. : 1033    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    21MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[19]
    Pathway No. : 1039    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    22MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[20]
    Pathway No. : 1045    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    23MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[21]
    Pathway No. : 1051    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    24MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[22]
    Pathway No. : 1057    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5
    25MAPK*  /
    MAPK*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• kinetics[23]
    Pathway No. : 1063    		25.6405104explicit E-S complexSubstrate
    PLA2-cytosolic

    Product
    PLA2*
        Km = 25uM @ 50 uM ATP and 1mg/ml MBP (huge XS of substrate) Vmax = 4124 pmol/min/ml at a conc of 125 pmol/ml of enz, so: k3 = .5/sec (rate limiting) k1 = (k2 + k3)/Km = (.5 + 0)/(25*6e5) = 2e-8 (#/cell)^-1 #s from Sanghera et al JBC 265 pp 52 , 1990. From Nemenoff et al JBC 268(3):1960-1964 - using Sanghera's 1e-4 ratio of MAPK to protein, we get k3 = 7/sec from 1000 pmol/min/mg fig 5

    PLA2-cytosolic acting as a Substrate in a reaction in      Ajay_Bhalla_2007_ReacDiff3 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    2PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 920    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    3PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 920    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    4diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    5PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 922    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    6PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 922    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    7diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    8PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 933    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    9PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 933    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    10diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    11PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 939    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    12PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 939    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    13diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    14PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 945    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    15PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 945    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    16diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    17PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 951    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    18PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 951    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    19diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    20PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 957    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    21PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 957    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    22diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    23PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 964    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    24PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 964    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    25diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    26PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 970    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    27PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 970    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    28diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    29PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 976    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    30PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 976    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    31diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    32PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 982    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    33PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 982    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    34diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    35PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 988    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    36PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 988    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    37diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    38PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 994    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    39PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 994    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    40diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    41PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1000    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    42PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1000    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    43diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    44PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1005    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    45PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1005    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    46diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    47PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1011    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    48PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1011    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    49diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    50PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1017    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    51PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1017    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    52diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    53PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1023    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    54PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1023    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    55diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    56PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1029    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    57PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1029    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    58diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    59PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1035    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    60PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1035    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    61diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    62PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1041    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    63PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1041    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    64diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    65PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1047    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    66PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1047    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    67diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    68PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1053    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    69PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1053    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    70diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    71PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1059    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    72PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1059    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*
    73PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1065    		1
    (uM^-1 s^-1)    		0.1
    (s^-1)    		Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    74PIP2-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1065    		0.0012
    (uM^-1 s^-1)    		0.5
    (s^-1)    		Kd(bf) = 416.6667(uM)-Substrate
    PLA2-cytosolic
    temp-PIP2

    Product
    PIP2-PLA2*

    PLA2-cytosolic acting as a Product in a reaction in      Ajay_Bhalla_2007_ReacDiff3 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    2
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 920    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    3diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    4
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 922    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    5diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    6
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 933    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    7diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    8
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 939    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    9diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    10
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 945    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    11diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    12
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 951    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    13diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    14
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 957    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    15
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1000    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    16diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    17
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 964    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    18diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    19
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 970    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    20diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    21
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 976    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    22diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    23
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 982    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    24diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    25
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 988    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    26diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    27
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 994    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    28diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    29diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    30
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1005    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    31diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    32
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1011    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    33diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    34
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1017    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    35diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    36
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1023    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    37diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    38
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1029    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    39diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    40
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1035    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    41diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    42
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1041    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    43diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    44
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1047    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    45diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    46
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1053    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    47diff
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3
    Pathway No. : 918
    		• 0.001
    (s^-1)    		0.001
    (s^-1)    		Keq = 1(uM)500secSubstrate
    PLA2-cytosolic

    Product
    PLA2-cytosolic
    48
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1059    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic
    49
  • dephosphorylate-
    PLA2*
  • Ajay_Bhalla_
    2007_ReacDiff3
    Accession No. : 84
    		• PLA2
    Pathway No. : 1065    		0.17
    (s^-1)    		0
    (s^-1)    		--Substrate
    PLA2*

    Product
    PLA2-cytosolic


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