NCBS Home page
Accession List
Pathway List
Search
Authorized Users
Help
News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.
Search in: Search for Match By

Molecule Parameter List for PLA2-Ca*

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network.
The text color of a molecule is highlighted by color.
Statistics
PLA2-Ca* participated asMoleculeSum total ofEnzymeSubstrate of an enzymeProduct of an enzymeSubstrate in ReactionProduct in Reaction
No. of occurrences25025007449

Accession and Pathway Details
Accession NameAccession No.Accession TypePathway Link
  • Ajay_Bhalla_
    2007_ReacDiff3
  • 84NetworkShared_Object_Ajay_Bhalla_2007_ReacDiff3 PKC PLA2 
    MAPK PLA2 Ras CaM chain kinetics PKC MAPK Ras CaM kinetics[1] 
    PKC PLA2 MAPK Ras CaM kinetics[2] PKC PLA2 MAPK Ras CaM kinetics[3] 
    PKC PLA2 MAPK Ras CaM kinetics[4] PKC PLA2 MAPK Ras CaM kinetics[5] 
    PKC PLA2 MAPK Ras MAPK CaM kinetics[6] PKC PLA2 MAPK Ras 
    CaM kinetics[7] PKC PLA2 MAPK Ras CaM PKC kinetics[8] PLA2 
    MAPK Ras CaM kinetics[9] PKC PLA2 MAPK Ras CaM kinetics[10] 
    PKC PLA2 MAPK Ras CaM kinetics[11] PKC PLA2 MAPK Ras CaM 
    kinetics[12] PKC PLA2 Ras CaM kinetics[13] PKC PLA2 MAPK 
    Ras CaM kinetics[14] PKC PLA2 MAPK Ras CaM kinetics[15] 
    PKC PLA2 MAPK Ras kinetics[16] CaM PKC PLA2 MAPK Ras CaM 
    kinetics[17] PKC PLA2 MAPK Ras CaM kinetics[18] PKC PLA2 
    MAPK Ras CaM kinetics[19] PKC PLA2 MAPK Ras CaM kinetics[20] 
    PKC PLA2 MAPK Ras CaM kinetics[21] PKC PLA2 MAPK Ras CaM 
    kinetics[22] PKC PLA2 MAPK Ras CaM kinetics[23] PKC PLA2 
    MAPK Ras CaM 
    This is a 25-compartment reaction-diffusion version of the Ajay_Bhalla_2007_bistable model. The original single-compartment model is repeated 25 times.
    In addition, a subset (33 out of 50) molecules can diffuse between compartments. Diffusion is implemented as a reaction between corresponding molecules in neighboring compartments. Here D = 1e-13 m^2/sec (i.e., 0.1 micron^2/sec ) so the kf and kb of this reaction for these 10 micron compartments are both 0.001/sec.
    The basal calcium level in this model is held at 95 nM which is rather close to threshold for the flip to the active state. This is necessary to sustain active propagation of activation.
    The stimulus file bis6-propgn_D1e-13_FigEF which was used for the model to replicate Figure 4E and 4F from the paper.

    PLA2-Ca* acting as a Molecule in  
    Ajay_Bhalla_2007_ReacDiff3 Network
    NameAccession NamePathway NameInitial Conc.
    (uM)
    Volume
    (fL)
    Buffered
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 920
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 922
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 933
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 939
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 945
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 951
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 957
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 964
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 970
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 976
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 982
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 988
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 994
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1000
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1005
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1011
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1017
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1023
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1029
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1035
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1041
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1047
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1053
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1059
    0125.7No
    PLA2-Ca*
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1065
    0125.7No

    PLA2-Ca* acting as an Enzyme in  
    Ajay_Bhalla_2007_ReacDiff3 Network
     Enzyme Molecule /
    Enzyme Activity
    Accession NamePathway NameKm (uM)kcat (s^-1)RatioEnzyme TypeReagents
    1PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 920
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    2PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 922
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    3PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 933
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    4PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 939
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    5PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 945
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    6PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 951
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    7PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 957
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    8PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 964
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    9PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 970
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    10PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 976
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    11PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 982
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    12PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 988
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    13PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 994
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    14PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1000
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    15PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1005
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    16PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1011
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    17PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1017
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    18PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1023
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    19PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1029
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    20PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1035
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    21PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1041
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    22PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1047
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    23PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1053
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    24PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1059
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3
    25PLA2-Ca* /
    kenz
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1065
    19.99945.44explicit E-S complexSubstrate
    APC

    Product
    AA
        10 x raise oct22 12 x oct 24, set k2 = 4 * k3

    PLA2-Ca* acting as a Substrate in a reaction in  
    Ajay_Bhalla_2007_ReacDiff3 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    2
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 920
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    3DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 920
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    4diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    5
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 922
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    6DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 922
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    7diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    8
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 933
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    9DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 933
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    10diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    11
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 939
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    12DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 939
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    13diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    14
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 945
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    15DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 945
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    16diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    17
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 951
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    18DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 951
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    19diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    20
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 957
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    21DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 957
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    22diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    23
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 964
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    24DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 964
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    25diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    26
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 970
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    27DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 970
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    28diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    29
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 976
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    30DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 976
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    31diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    32
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 982
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    33DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 982
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    34diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    35
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 988
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    36DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 988
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    37diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    38
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 994
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    39DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 994
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    40diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    41
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1000
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    42DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1000
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    43diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    44
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1005
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    45DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1005
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    46diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    47
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1011
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    48DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1011
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    49diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    50
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1017
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    51DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1017
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    52diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    53
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1023
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    54DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1023
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    55diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    56
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1029
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    57DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1029
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    58diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    59
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1035
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    60DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1035
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    61diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    62
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1041
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    63DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1041
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    64diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    65
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1047
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    66DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1047
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    67diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    68
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1053
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    69DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1053
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    70diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    71
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1059
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    72DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1059
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.
    73
  • PIP2-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1065
    0.012
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 8.3333(uM)-Substrate
    PLA2-Ca*
    temp-PIP2

    Product
    PIP2-Ca-PLA2*
    74DAG-Ca-PLA2-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1065
    0.003
    (uM^-1 s^-1)
    4
    (s^-1)
    Kd(bf) = 1333.3289(uM)-Substrate
    DAG
    PLA2-Ca*

    Product
    DAG-Ca-PLA2*
      27 June 1996 Scaled kf down by 0.015 from 3.33e-7 to 5e-9 to fit with revised DAG estimates and use of mole-fraction to calculate eff on PLA2.

    PLA2-Ca* acting as a Product in a reaction in  
    Ajay_Bhalla_2007_ReacDiff3 Network
    Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reaction are not consider.
     NameAccession NamePathway NameKfKbKdtauReagents
    1PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 920
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    2diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    3PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 922
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    4diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    5PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 933
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    6diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    7PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 939
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    8diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    9PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 945
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    10diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    11PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 951
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    12diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    13PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 957
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    14diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    15PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 964
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    16diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    17PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 970
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    18diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    19PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 976
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    20diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    21PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 982
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    22diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    23PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 988
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    24diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    25PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 994
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    26diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    27PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1000
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    28diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    29PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1005
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    30diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    31PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1011
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    32diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    33PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1017
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    34diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    35PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1023
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    36diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    37PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1029
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    38diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    39PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1035
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    40diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    41PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1041
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    42diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    43PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1047
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    44diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    45PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1053
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    46diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    47PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1059
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.
    48diff
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • Shared_Object_
    Ajay_Bhalla_
    2007_ReacDiff3

    Pathway No. : 918
  • 0.001
    (s^-1)
    0.001
    (s^-1)
    Keq = 1(uM)500secSubstrate
    PLA2-Ca*

    Product
    PLA2-Ca*
    49PLA2-Ca-act
  • Ajay_Bhalla_
    2007_ReacDiff3

    Accession No. : 84
  • PLA2
    Pathway No. : 1065
    1
    (uM^-1 s^-1)
    0.1
    (s^-1)
    Kd(bf) = 0.1(uM)-Substrate
    Ca
    PLA2-cytosolic

    Product
    PLA2-Ca*
      Leslie and Channon BBA 1045 (1990) 261-270 fig6 pp267.



    Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
    This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.