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Accession Type:
Network

fig2_egfr

Shared_Object_
fig2_egfr

		Ras
		Molecule
		Enzyme
		Reaction

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Reaction List for pathway Ras (Pathway Number 7)

Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered.

	Name	Kf	Kb	Kd	tau	Substrate	Product
1	bg-act-GEF	6 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.1667(uM)	-	BetaGamma inact-GEF	GEF-Gprot-bg
2	CaM-bind-GEF	60 (uM^-1 s^-1)	1 (s^-1)	Kd(bf) = 0.0167(uM)	-	inact-GEF CaM-Ca4	CaM-GEF
3	dephosph-GAP	0.1 (s^-1)	0 (s^-1)	-	-	GAP*	GAP
4	dephosph-GEF	1 (s^-1)	0 (s^-1)	-	-	GEF*	inact-GEF
5	dephosph-inact-G EF*	1 (s^-1)	0 (s^-1)	-	-	inact-GEF*	inact-GEF
6	Ras-intrinsic-GT Pase	0.0001 (s^-1)	0 (s^-1)	-	-	GTP-Ras	GDP-Ras

Pathway Details Molecule List Enzyme List Reaction List

Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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