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Molecule Parameter List for actCaMKII-PSD

The statistics table lists the distribution of a molecule acting either as a substrate, product, enzyme or as a molecule within the network. The text color of a molecule is highlighted by color.

Statistics

actCaMKII-PSD participated as	Molecule	Sum total of	Enzyme	Substrate of an enzyme	Product of an enzyme	Substrate in Reaction	Product in Reaction
No. of occurrences	1	3	16	0	0	0	0

Accession and Pathway Details

Accession Name	Accession No.	Accession Type	Pathway Link
AMPAR_CaMKII_ weak_coupling	65	Network	Shared_Object_AMPAR_CaMKII_weak_coupling,  CaMKII,  CaM,   PP1,  PP2B,  PP1_PSD,   AMPAR,  PKA,  AC,   AMPAR_memb,  PP1_CaMKII_PSD,  CaMKII_PSD
This is a model of weak coupling between the AMPAR traffikcing bistability, and the CaMKII autophosphorylation bistability. In this model, there are three stable states: Both off, AMPAR on, or both on. The fourth possible state: CaMKII on but AMPAR off, is not truly stable, since over the course of hours the AMPAR also turns on.

actCaMKII-PSD acting as a Molecule in  AMPAR_CaMKII_weak_coupling Network

Name	Accession Name	Pathway Name	Initial Conc. (uM)	Volume (fL)	Buffered
actCaMKII-PSD	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	2	0.01	No

actCaMKII-PSD acting as a Summed Molecule in  AMPAR_CaMKII_weak_coupling Network

	Accession Nane	Pathway Name	Target	Input
1	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	tot_CaMKII_PSD	actCaMKII-PSD CaMKII-PSD CaMKII-thr305-PS D
2	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	actCaMKII-PSD	CaMKII-thr286-Ca M-PSD CaMKII-CaM-PSD tot-auto-PSD
3	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	tot-auto-PSD	CaMKII-thr286-PS D CaMKII***-PSD basal_CaMKII_ PSD

actCaMKII-PSD acting as an Enzyme in  AMPAR_CaMKII_weak_coupling Network

	Enzyme Molecule / Enzyme Activity	Accession Name	Pathway Name	Km (uM)	kcat (s^-1)	Ratio	Enzyme Type	Reagents
1	actCaMKII-PSD / CaMKII	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A845*_B845* Product A831*845*_B845*
2	actCaMKII-PSD / CaMKII[1]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A_B845* Product A831*_B845*
3	actCaMKII-PSD / CaMKII[2]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A845*_B Product A831*845*_B
4	actCaMKII-PSD / CaMKII[3]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A_B Product A831*_B
5	actCaMKII-PSD / CaMKII[4]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A845*_B845* Product A845*_B831*845*
6	actCaMKII-PSD / CaMKII[5]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A_B845* Product A_B831*845*
7	actCaMKII-PSD / CaMKII[6]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A845*_B Product A845*_B831*
8	actCaMKII-PSD / CaMKII[7]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A_B Product A_B831*
9	actCaMKII-PSD / CaMKII[8]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A845*_B831*845* Product A835*845*_ B835*845*
10	actCaMKII-PSD / CaMKII[9]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A_B831*845* Product A831*_B831*845*
11	actCaMKII-PSD / CaMKII[10]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A845*_B831* Product A831*845*_B831*
12	actCaMKII-PSD / CaMKII[11]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A_B831* Product A831*_B831*
13	actCaMKII-PSD / CaMKII[12]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A831*845*_B845* Product A835*845*_ B835*845*
14	actCaMKII-PSD / CaMKII[13]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A831*_B845* Product A831*_B831*845*
15	actCaMKII-PSD / CaMKII[14]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A831*845*_B Product A831*845*_B831*
16	actCaMKII-PSD / CaMKII[15]	AMPAR_CaMKII_ weak_coupling Accession No. : 65	CaMKII_PSD Pathway No. : 292	90.0006	0.5	4	explicit E-S complex	Substrate A831*_B Product A831*_B831*