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Reaction List for pathway Gq (Pathway Number 5) |
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered. |
| Name | Kf | Kb | Kd | tau | Substrate | Product | |
| 1 | Activate-Gq | 0.01 (s^-1) | 0 (uM^-2 s^-1) | - | - | Rec-Glu-Gq | G*GTP BetaGamma Rec-Glu |
| 2 | Antag-bind-Rec-G q | 60 (uM^-1 s^-1) | 0.01 (s^-1) | Kd(bf) = 0.0002(uM) | - | Rec-Gq mGluRAntag | Blocked-rec-Gq |
| 3 | Basal-Act-G | 0.0001 (s^-1) | 0 (uM^-1 s^-1) | - | - | G-GDP | G*GTP BetaGamma |
| 4 | Glu-bind-Rec-Gq | 16.8 (uM^-1 s^-1) | 0.1 (s^-1) | Kd(bf) = 0.006(uM) | - | Glu Rec-Gq | Rec-Glu-Gq |
| 5 | Inact-G | 0.0133 (s^-1) | 0 (s^-1) | - | - | G*GTP | G*GDP |
| 6 | Rec-bind-Gq | 0.6 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 1.6667(uM) | - | G-GDP mGluR | Rec-Gq |
| 7 | Rec-Glu-bind-Gq | 0.006 (uM^-1 s^-1) | 0.0001 (s^-1) | Kd(bf) = 0.0167(uM) | - | G-GDP Rec-Glu | Rec-Glu-Gq |
| 8 | RecLigandBinding | 16.8 (uM^-1 s^-1) | 10 (s^-1) | Kd(bf) = 0.5952(uM) | - | mGluR Glu | Rec-Glu |
| 9 | Trimerize-G | 6 (uM^-1 s^-1) | 0 (s^-1) | - | - | G*GDP BetaGamma | G-GDP |
| Pathway Detail | Molecule List | Enzyme List | Reaction List |