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Parameters for MAPK (Pathway Number 193)

Pathway Layout

Pathway Basic Parameters

Pathway NameMAPK
Pathway Entry Number 193
Accession Number 45
Accession Name MAPK_Asthagiri_adapt_fb
Species Chinese hamster (Cricetulus griseus); mammalian
Tissue Ovary - CHO cell line
CellCompartment Surface, cytosol
Related Pathways 6, 24, 35, 56, 61, 75, 139, 142, 182, 211, 230, 317, 335, 352, 366, 371, 377, 384, 390, 396, 402, 403, 409, 415, 421, 432, 438, 444, 450, 456, 462, 468, 474, 480, 486, 492, 498, 504, 510, 516, 522, 528, 535, 541, 547, 553, 559, 565, 571, 577, 583, 589, 595, 601, 607, 613, 619, 625, 631, 637, 643, 649, 655, 661, 667, 673, 679, 686, 692, 699, 704, 710, 716, 722, 728, 734, 740, 746, 752, 758, 764, 770, 776, 782, 788, 794, 800, 806, 812, 818, 824, 830, 836, 842, 848, 854, 860, 866, 872, 878, 884, 890, 896, 902, 908, 914, 921, 928, 934, 940, 946, 952, 958, 960, 965, 971, 977, 983, 989, 995, 1006, 1012, 1018, 1024, 1030, 1036, 1042, 1048, 1054, 1060, 1066, 1103
Notes  This is a complex model to examine mechanisms that govern MAPK pathway dynamics in Chinese hamster ovary (CHO) cell lines, particularly the role of adapter targeted negative feedback mechanism in generating complete signal adaptation. This model simulates the results as per the figure 7A of the paper by Asthagiri AR and Lauffenburger DA. Biotechnol Prog. (2001) 17(2):227-39.

Statistics

26
11
7

Conversion format

This pathway is part of accession 45 and is completely specified in the file acc45.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc45.g   
GENESIS Format (Annotated version)    Anno_acc45.g   
MATLAB format    acc45.m   
SBML format    acc45.xml   
Pathway DetailMolecule ListEnzyme ListReaction List