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Accession Type:
Network
fig3_CaMKII
Shared_Object_
fig3_CaMKII
CaMKII
 Molecule
 Enzyme
 Reaction
CaM
PP1
PP2B
PKA
AC

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Parameters for CaMKII (Pathway Number 13)

Pathway Layout

Pathway Basic Parameters

Pathway NameCaMKII
Pathway Entry Number 13
Accession Number 2
Accession Name fig3_CaMKII
Species Generic mammalian
Tissue Neuronal
CellCompartmentSynapse
Related Pathways 26, 80, 106, 121, 145, 159, 174, 202, 216, 235, 245, 258, 264, 272, 282, 322, 339, 357
Notes  This is the model file for figure 3 from Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It is a model of the Ca activation of CaMKII and other CaM-activated enzymes. It includes the regulatory phosphatases PP1 and PP2B (Calcineurin) acting on CaMKII and also includes CaM-activated adenylyl cyclase and PKA in the synapse.
Demonstration script files for generating the figures in the paper, including figure 3, are available here.

Statistics

9
4
3

Conversion format

This pathway is part of accession 2 and is completely specified in the file acc2.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc2.g   
GENESIS Format (Annotated version)    Anno_acc2.g   


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Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
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