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Pathway List for CamKII

Default ordering is done according to Pathway Name.Table header can be used for changing the default ordering.
indicates that ordering is done according to ascending or descending order.
Entries are color tagged depending on Network  or Pathway 
#3#3#3#2#2#1#19#19#19#1#19#1#1#1#19#1#19#1#19#19
  Pathway Name
Pathway No.		Accession Name
Accession No.		Accession
Type		Pathway statisticsCamKII statisticsSource
Entry Date
1 CaMKIII_g
Pathway No. 1159		 syn_CaMKIII

Accession No. 114		PathwayMolecule = 2
Enzyme   = 0
Reaction  = 0
Molecule = 2
Enzyme   = 0
Reaction  = 0
Bhalla US. PLoS Comput Biol 2021 Nov 29;17(11):e1009621. /
2022-10-01 00:12:23
   Related Pathway: 
1145, 1151
    This model was used to generate Fig 3 supp A to F in Bhalla US. HillTau: A fast, compact abstraction for model reduction in biochemical signaling networks. PLoS Comput Biol 2021 Nov 29;17(11):e1009621.
   
This pathway is part of accession 114 and is completely specified in the file acc114.g.
There is no separate file for just this pathway.
FormatFile
HillTau format    acc114.json   
2 CaMKIII_g
Pathway No. 1151		 aut6

Accession No. 110		PathwayMolecule = 3
Enzyme   = 0
Reaction  = 0
Molecule = 3
Enzyme   = 0
Reaction  = 0
Bhalla US. PLoS Comput Biol 2021 Nov 29;17(11):e1009621. /
2022-10-01 00:02:13
   Related Pathway: 
1145, 1159
    This model was used to generate Fig 6 in Bhalla US. HillTau: A fast, compact abstraction for model reduction in biochemical signaling networks. PLoS Comput Biol 2021 Nov 29;17(11):e1009621.
   
This pathway is part of accession 110 and is completely specified in the file acc110.g.
There is no separate file for just this pathway.
FormatFile
HillTau format    acc110.json   
3 CaMKIII_g
Pathway No. 1145		 syn_prot_
composite
Accession No. 109		PathwayMolecule = 2
Enzyme   = 0
Reaction  = 0
Molecule = 2
Enzyme   = 0
Reaction  = 0
Bhalla US. PLoS Comput Biol 2021 Nov 29;17(11):e1009621. /
2022-09-30 23:58:38
   Related Pathway: 
1151, 1159
    This model was used to generate fig 5 D to k, fig 6 in Bhalla US. HillTau: A fast, compact abstraction for model reduction in biochemical signaling networks. PLoS Comput Biol 2021 Nov 29;17(11):e1009621.
   
This pathway is part of accession 109 and is completely specified in the file acc109.g.
There is no separate file for just this pathway.
FormatFile
HillTau format    acc109.json   
4 CaMKII_g
Pathway No. 1142		 bcm_bistable

Accession No. 108		PathwayMolecule = 4
Enzyme   = 0
Reaction  = 0
Molecule = 3
Enzyme   = 0
Reaction  = 0
Bhalla US. PLoS Comput Biol 2021 Nov 29;17(11):e1009621. /
2022-09-30 23:49:58
   Related Pathway: 
1138
    This model was used to generate Fig 3 G in Bhalla US. HillTau: A fast, compact abstraction for model reduction in biochemical signaling networks. PLoS Comput Biol 2021 Nov 29;17(11):e1009621.
   
This pathway is part of accession 108 and is completely specified in the file acc108.g.
There is no separate file for just this pathway.
FormatFile
HillTau format    acc108.json   
5 CaMKII_g
Pathway No. 1138		 bcm

Accession No. 107		PathwayMolecule = 2
Enzyme   = 0
Reaction  = 0
Molecule = 2
Enzyme   = 0
Reaction  = 0
Bhalla US.PLoS Comput Biol 2021 Nov 29;17(11):e1009621./
2022-09-30 23:36:25
   Related Pathway: 
1142
    This model was used to generate Fig 3 C, D ,E, Fig 6,Fig7 supp C in Bhalla US. HillTau: A fast, compact abstraction for model reduction in biochemical signaling networks. PLoS Comput Biol 2021 Nov 29;17(11):e1009621.
   
This pathway is part of accession 107 and is completely specified in the file acc107.g.
There is no separate file for just this pathway.
FormatFile
HillTau format    acc107.json   
6 
  • Shared_Object_
    CaMKIII
    Pathway No. 1093
    		•  CaMKIII

    Accession No. 90    		NetworkMolecule = 15
    Enzyme   = 5
    Reaction  = 3
    		Molecule = 4
    Enzyme   = 4
    Reaction  = 2
    		Jain P, and Bhalla, U.S. PLoS Comput Biol. 2009 Feb;5(2). ( Peer-reviewed publication )/
    2009-02-12 00:00:00
       Related Pathway: ------
        CaMKIII is activated by Ca2+ and inactivated by S6K. Since CaMKIII inhibits eEF2, the net effect of Ca2+ on elongation is inhibitory and of S6K is excitatory
       
    This pathway is part of accession 90 and is completely specified in the file acc90.g.
    There is no separate file for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc90.g   
    7 CaMKII
    Pathway No. 357    		 Ajay_Bhalla_
    2004_Feedback_
    Tuning
    Accession No. 78    		NetworkMolecule = 8
    Enzyme   = 4
    Reaction  = 3
    		Molecule = 7
    Enzyme   = 4
    Reaction  = 1
    		Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. ( Peer-reviewed publication )/
    2006-12-12 00:00:00
       Related Pathway: 
    13, 26, 80, 106, 121, 145, 159, 174, 202, 216, 235, 245, 258, 264, 272, 282, 322, 339
        Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzs look a terrible mess. Actually it is just 3 reactions for diff sites, by 4 states of CaMKII, defined by the phosph state.
       
    This pathway is part of accession 78 and is completely specified in the file acc78.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc78.g   
    MATLAB format    acc78.m   
    SBML format    acc78.xml   
    8 CaMKII
    Pathway No. 339    		 Ajay_Bhalla_
    2004_PKM_MKP3_
    Tuning
    Accession No. 77    		NetworkMolecule = 8
    Enzyme   = 4
    Reaction  = 3
    		Molecule = 7
    Enzyme   = 4
    Reaction  = 1
    		Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80 ( Peer-reviewed publication )/
    2006-12-12 00:00:00
       Related Pathway: 
    13, 26, 80, 106, 121, 145, 159, 174, 202, 216, 235, 245, 258, 264, 272, 282, 322, 357
        Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzs look a terrible mess. Actually it is just 3 reactions for diff sites, by 4 states of CaMKII, defined by the phosph state.
       
    This pathway is part of accession 77 and is completely specified in the file acc77.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc77.g   
    MATLAB format    acc77.m   
    SBML format    acc77.xml   
    9 CaMKII
    Pathway No. 322    		 Ajay_Bhalla_
    2004_PKM_Tuning
    Accession No. 76    		NetworkMolecule = 8
    Enzyme   = 4
    Reaction  = 3
    		Molecule = 7
    Enzyme   = 4
    Reaction  = 1
    		Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. ( Peer-reviewed publication )/
    2006-12-12 00:00:00
       Related Pathway: 
    13, 26, 80, 106, 121, 145, 159, 174, 202, 216, 235, 245, 258, 264, 272, 282, 339, 357
        Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzs look a terrible mess. Actually it is just 3 reactions for diff sites, by 4 states of CaMKII, defined by the phosph state.
       
    This pathway is part of accession 76 and is completely specified in the file acc76.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc76.g   
    MATLAB format    acc76.m   
    SBML format    acc76.xml   
    10 
  • Shared_Object_
    AMPAR_CaMKII_
    weak_coupling
    Pathway No. 281
    		•  AMPAR_CaMKII_
    weak_coupling
    Accession No. 65    		NetworkMolecule = 30
    Enzyme   = 14
    Reaction  = 8
    		Molecule = 0
    Enzyme   = 0
    Reaction  = 0
    		Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
    2005-07-21 00:00:00
       Related Pathway: ------
        This is a model of weak coupling between the AMPAR traffikcing bistability, and the CaMKII autophosphorylation bistability. In this model, there are three stable states: Both off, AMPAR on, or both on. The fourth possible state: CaMKII on but AMPAR off, is not truly stable, since over the course of hours the AMPAR also turns on.
       
    This pathway is part of accession 65 and is completely specified in the file acc65.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc65.g   
    MATLAB format    acc65.m   
    SBML format    acc65.xml   
    11 CaMKII
    Pathway No. 282    		 AMPAR_CaMKII_
    weak_coupling
    Accession No. 65    		NetworkMolecule = 11
    Enzyme   = 4
    Reaction  = 2
    		Molecule = 10
    Enzyme   = 4
    Reaction  = 1
    		Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
    2005-07-21 00:00:00
       Related Pathway: 
    13, 26, 80, 106, 121, 145, 159, 174, 202, 216, 235, 245, 258, 264, 272, 322, 339, 357
        Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzs look a terrible mess. Actually it is just 3 reactions for diff sites, by 4 states of CaMKII, defined by the phosph state.
       
    This pathway is part of accession 65 and is completely specified in the file acc65.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc65.g   
    MATLAB format    acc65.m   
    SBML format    acc65.xml   
    12 PP1_CaMKII_PSD
    Pathway No. 291    		 AMPAR_CaMKII_
    weak_coupling
    Accession No. 65    		NetworkMolecule = 1
    Enzyme   = 5
    Reaction  = 0
    		Molecule = 1
    Enzyme   = 5
    Reaction  = 0
    		Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
    2005-07-21 00:00:00
       Related Pathway: ------
        This is a model of weak coupling between the AMPAR traffikcing bistability, and the CaMKII autophosphorylation bistability. In this model, there are three stable states: Both off, AMPAR on, or both on. The fourth possible state: CaMKII on but AMPAR off, is not truly stable, since over the course of hours the AMPAR also turns on.
       
    This pathway is part of accession 65 and is completely specified in the file acc65.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc65.g   
    MATLAB format    acc65.m   
    SBML format    acc65.xml   
    13 CaMKII_PSD
    Pathway No. 292    		 AMPAR_CaMKII_
    weak_coupling
    Accession No. 65    		NetworkMolecule = 14
    Enzyme   = 22
    Reaction  = 8
    		Molecule = 11
    Enzyme   = 19
    Reaction  = 4
    		Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
    2005-07-21 00:00:00
       Related Pathway: ------
        This is a model of weak coupling between the AMPAR traffikcing bistability, and the CaMKII autophosphorylation bistability. In this model, there are three stable states: Both off, AMPAR on, or both on. The fourth possible state: CaMKII on but AMPAR off, is not truly stable, since over the course of hours the AMPAR also turns on.
       
    This pathway is part of accession 65 and is completely specified in the file acc65.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc65.g   
    MATLAB format    acc65.m   
    SBML format    acc65.xml   
    14 
  • Shared_Object_
    AMPAR_CaMKII_
    strong_coupling
    Pathway No. 271
    		•  AMPAR_CaMKII_
    strong_coupling
    Accession No. 64    		NetworkMolecule = 51
    Enzyme   = 148
    Reaction  = 16
    		Molecule = 14
    Enzyme   = 19
    Reaction  = 4
    		Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
    2005-07-19 00:00:00
       Related Pathway: ------
        This is a model of tight coupling between the AMPAR trafficking bistability, and the CaMKII autophosphorylation bistability. In this model, the CaMKII activity is self sustaining only when AMPAR is turned on. Further, CaMKII turns on when AMPAR is turned on.
       
    This pathway is part of accession 64 and is completely specified in the file acc64.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc64.g   
    MATLAB format    acc64.m   
    SBML format    acc64.xml   
    15 CaMKII
    Pathway No. 272    		 AMPAR_CaMKII_
    strong_coupling
    Accession No. 64    		NetworkMolecule = 8
    Enzyme   = 4
    Reaction  = 2
    		Molecule = 7
    Enzyme   = 4
    Reaction  = 1
    		Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
    2005-07-19 00:00:00
       Related Pathway: 
    13, 26, 80, 106, 121, 145, 159, 174, 202, 216, 235, 245, 258, 264, 282, 322, 339, 357
        Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzs look a terrible mess. Actually it is just 3 reactions for diff sites, by 4 states of CaMKII, defined by the phosph state.
       
    This pathway is part of accession 64 and is completely specified in the file acc64.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc64.g   
    MATLAB format    acc64.m   
    SBML format    acc64.xml   
    16 
  • Shared_Object_
    CaMKII_model3
    Pathway No. 263
    		•  CaMKII_model3

    Accession No. 63    		NetworkMolecule = 36
    Enzyme   = 30
    Reaction  = 14
    		Molecule = 14
    Enzyme   = 3
    Reaction  = 4
    		Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
    2005-07-19 00:00:00
       Related Pathway: ------
        This is the complete model of CaMKII bistability, model 3. It exhibits bistability in CaMKII activation due to autophosphorylation at the PSD and local saturation of PP1. This version of model 3 includes PKA regulatory input. This has little effect on the deterministic calculations, but the PKA pathway introduces a lot of noise which causes a difference in stochastic runs.
       
    This pathway is part of accession 63 and is completely specified in the file acc63.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc63.g   
    MATLAB format    acc63.m   
    SBML format    acc63.xml   
    17 CaMKII
    Pathway No. 264    		 CaMKII_model3

    Accession No. 63    		NetworkMolecule = 8
    Enzyme   = 4
    Reaction  = 2
    		Molecule = 7
    Enzyme   = 4
    Reaction  = 1
    		Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
    2005-07-19 00:00:00
       Related Pathway: 
    13, 26, 80, 106, 121, 145, 159, 174, 202, 216, 235, 245, 258, 272, 282, 322, 339, 357
        Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzs look a terrible mess. Actually it is just 3 reactions for diff sites, by 4 states of CaMKII, defined by the phosph state.
       
    This pathway is part of accession 63 and is completely specified in the file acc63.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc63.g   
    MATLAB format    acc63.m   
    SBML format    acc63.xml   
    18 
  • Shared_Object_
    CaMKII_noPKA_
    model3
    Pathway No. 257
    		•  CaMKII_noPKA_
    model3
    Accession No. 62    		NetworkMolecule = 33
    Enzyme   = 28
    Reaction  = 13
    		Molecule = 14
    Enzyme   = 3
    Reaction  = 4
    		Hayer A, Bhalla US PLoS PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
    2005-07-19 00:00:00
       Related Pathway: ------
        This is the model of CaMKII bistability, model 3. It exhibits bistability in CaMKII activation due to autophosphorylation at the PSD and local saturation of PP1. This version of model 3 does not include the full PKA regulatory pathway, and instead has a predefined initial amount of active PKA.
       
    This pathway is part of accession 62 and is completely specified in the file acc62.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc62.g   
    MATLAB format    acc62.m   
    SBML format    acc62.xml   
    19 CaMKII
    Pathway No. 258    		 CaMKII_noPKA_
    model3
    Accession No. 62    		NetworkMolecule = 8
    Enzyme   = 4
    Reaction  = 2
    		Molecule = 7
    Enzyme   = 4
    Reaction  = 1
    		Hayer A, Bhalla US PLoS PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
    2005-07-19 00:00:00
       Related Pathway: 
    13, 26, 80, 106, 121, 145, 159, 174, 202, 216, 235, 245, 264, 272, 282, 322, 339, 357
        Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzs look a terrible mess. Actually it is just 3 reactions for diff sites, by 4 states of CaMKII, defined by the phosph state.
       
    This pathway is part of accession 62 and is completely specified in the file acc62.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc62.g   
    MATLAB format    acc62.m   
    SBML format    acc62.xml   
    20 CaMKII
    Pathway No. 245    		 AMPAR_traff_
    model1
    Accession No. 60    		NetworkMolecule = 25
    Enzyme   = 24
    Reaction  = 10
    		Molecule = 21
    Enzyme   = 22
    Reaction  = 5
    		Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
    2005-07-19 00:00:00
       Related Pathway: 
    13, 26, 80, 106, 121, 145, 159, 174, 202, 216, 235, 258, 264, 272, 282, 322, 339, 357
        Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzs look a terrible mess. Actually it is just 3 reactions for diff sites, by 4 states of CaMKII, defined by the phosph state.
       
    This pathway is part of accession 60 and is completely specified in the file acc60.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc60.g   
    MATLAB format    acc60.m   
    SBML format    acc60.xml   
     
    Result: 1 - 20 of 34 rows are displayed Previous of 2  Next


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