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Reaction List for pathway PLCbeta (Pathway Number 67) |
| Kd is calculated only for second order reactions, like nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules, where as for first order reactions Keq is calculated. Kd for higher order reactions is not considered. |
| Name | Kf | Kb | Kd | tau | Substrate | Product | |
| 1 | Basal | 0.009 (s^-1) | 0 (uM^-1 s^-1) | - | - | PIP2 | DAG IP3 |
| 6 Nov 2001 The basal reaction rates are fixed according to the respomse curves obtained from I. Litosch, Biochem.,2000, 39, 7736-7743. | |||||||
| 2 | Ca_bind_PLCbeta | 1 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 1(uM) | - | Ca PLCbeta | Ca.PLCbeta |
| 6 Nov 2001 The Kf and Kb values were fixed according to the dose response curves obtained from I.Litosch, Biochem., 2000, 39, 7736-7743. | |||||||
| 3 | Gq-bind-Ca.PLCbe ta | 50 (uM^-1 s^-1) | 1 (s^-1) | Kd(bf) = 0.02(uM) | - | Gq Ca.PLCbeta | Gq.Ca.PLCbeta |
| 6 Nov 2001 The Kf and Kb values were fixed according to the response curves obtained from I. Litosch, Biochem., 2000, 39, 7736-7743. | |||||||
| 4 | PA-bind-Ca.PLCbe ta | 1 (uM^-1 s^-1) | 8 (s^-1) | Kd(bf) = 8(uM) | - | PA Ca.PLCbeta | PA.Ca.PLCbeta |
| 6 Nov 2001 The Kf and Kb values were fixed according to the dose response curves obtained from I. Litosch, Biochem., 2000, 39, 7736-7743. | |||||||
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