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Accession Type:
Network
MAPK_MKP1_
oscillation
Shared_Object_
MAPK_MKP1_
oscillation
PKC
MAPK
 Molecule
 Enzyme
 Reaction
PLA2
Ras

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Parameters for MAPK (Pathway Number 61)

Pathway Layout

Pathway Basic Parameters

Pathway NameMAPK
Pathway Entry Number 61
Accession Number 9
Accession Name MAPK_MKP1_oscillation
Species Generic mammalian
Tissue NIH 3T3 Expression
CellCompartmentSurface - Nucleus
Related Pathways 6, 24, 35, 56, 75, 139, 142, 182, 193, 211, 230, 317, 335, 352, 366, 371, 377, 384, 390, 396, 402, 403, 409, 415, 421, 432, 438, 444, 450, 456, 462, 468, 474, 480, 486, 492, 498, 504, 510, 516, 522, 528, 535, 541, 547, 553, 559, 565, 571, 577, 583, 589, 595, 601, 607, 613, 619, 625, 631, 637, 643, 649, 655, 661, 667, 673, 679, 686, 692, 699, 704, 710, 716, 722, 728, 734, 740, 746, 752, 758, 764, 770, 776, 782, 788, 794, 800, 806, 812, 818, 824, 830, 836, 842, 848, 854, 860, 866, 872, 878, 884, 890, 896, 902, 908, 914, 921, 928, 934, 940, 946, 952, 958, 960, 965, 971, 977, 983, 989, 995, 1006, 1012, 1018, 1024, 1030, 1036, 1042, 1048, 1054, 1060, 1066
Notes  This model relates to figure 5 in Bhalla US, Iyengar R. Chaos (2001) 11(1):221-226. It includes the model used for figures 2-4 and also has MKP-1 induction by MAPK activity in the synapse. PP2A is set to 0.16 uM and MKP synthesis is varied from 5x to 40 x basal to get a range of interesting behaviours.

Statistics

15
9
7

Conversion format

This pathway is part of accession 9 and is completely specified in the file acc9.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc9.g   
GENESIS Format (Annotated version)    Anno_acc9.g   
GENESIS Format (Annotated version)    Anno_acc9.g   
MATLAB format    acc9.m   
SBML format    acc9.xml   


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Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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