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Accession Type:
Network
Synaptic_
Network
Shared_Object_
Synaptic_
Network
PKC
PLA2
PLCbeta
Gq
 Molecule
 Reaction
MAPK
Ras
EGFR
Sos
PLC_g
CaMKII
CaM
PP1
PP2B
PKA
AC
CaRegulation

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Parameters for Gq (Pathway Number 74)

Pathway Layout

Pathway Basic Parameters

Pathway NameGq
Pathway Entry Number 74
Accession Number 16
Accession Name Synaptic_Network
Species Generic mammalian
Tissue Neuronal
CellCompartmentSynapse
Related Pathways 5, 23, 111, 125, 150, 163, 210, 316, 334, 351
Notes The model for the Gq pathway plus its activators, here represented by the metabotropic glutamate receptor. We assume GTP is present in fixed amounts, so we leave it out of the explicit equations in this model. Normally we would expect it to associate along with the G-Receptor-ligand complex. Most info is from Berstein et al JBC 267:12 8081-8088 1992 Structure of receptor activation of Gq from Fay et al Biochem 30 5066-5075 1991 This mGluR/Gq model lacks a mechanism for receptor desensitization.

Statistics

Enzyme sites
7
0
9

Conversion format

This pathway is part of accession 16 and is completely specified in the file acc16.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc16.g   
GENESIS Format (Annotated version)    Anno_acc16.g   


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Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
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