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Accession Type:
Network

AMPAR_CaMKII_
weak_coupling

Shared_Object_
AMPAR_CaMKII_
weak_coupling

PP1_CaMKII_PSDPP1_CaMKII_PSD

		CaMKII_PSD
		Molecule
		Enzyme
		Reaction

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Molecule List for pathway CaMKII_PSD (Pathway Number 292)

	Name	Initial Conc. (uM)	Volume (fL)	Buffered
1	286P-PSD	0	0.01	No

2	actCaMKII-PSD	2	0.01	No

3	basal_CaMKII_PSD	2	0.01	No

4	basal_CaMKII_PSD_control	2	0.01	Yes

5	CaMKII***-PSD	0	0.01	No

6	CaMKII-CaM-PSD	0	0.01	No

7	CaMKII-PSD	0	0.01	No

8	CaMKII-thr286-CaM-PSD	0	0.01	No

9	CaMKII-thr286-PSD	0	0.01	No

10	CaMKII-thr305-PSD	0	0.01	No

11	NMDAR	120	0.01	No
	The stochiometry is a bit off here. Each NMDAR actually binds to a holoenzyme, about 12 CaMKII subunits. But our CaMKII calculations are in terms of individual subunits. So as a hack, we put in much more NMDAR than is actually there.
12	tot-auto-PSD	2	0.01	No

13	tot-CaM-CaMKII-PSD	0	0.01	No

14	tot_CaMKII_PSD	2	0.01	No

Summed Molecule List

	Target	Inputs
1	286P-PSD	CaMKII-thr286-Ca M-PSD CaMKII-thr286-PS D
2	actCaMKII-PSD	CaMKII-thr286-Ca M-PSD CaMKII-CaM-PSD tot-auto-PSD
3	tot-auto-PSD	CaMKII-thr286-PS D CaMKII***-PSD basal_CaMKII_ PSD
4	tot-CaM-CaMKII-PSD	CaMKII-thr286-Ca M-PSD CaMKII-CaM-PSD
5	tot_CaMKII_PSD	actCaMKII-PSD CaMKII-PSD CaMKII-thr305-PS D

Pathway Details Molecule List Enzyme List Reaction List

Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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