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| Accession No. | Name![]() | Source / Entry Date | Species / Tissue | Cell Compartment | Methodology / Model Implementation |
| 52 | pathway | Quantification of Short Term Signaling by the EGFR Kholodenko et al, The J Biol Chem. , Vol 274, No. 42, Issue of October 15, pp. 30169 - 30181, 1999. ( peer-reviewed publication ) / 2003-05-17 00:00:00 | Harlan Sprague Dawley rat; mammalian / Hepatocytes | Cell membrane + cytosol | Qualitative / Mathematically equivalent |
| 97 | exc | Bhalla US.PLoS Comput Biol 2021 Nov 29;17(11):e1009621. / 2022-09-30 15:13:55 | Generic / | cytosol | Fit to elementary ODE model / HillTau implementation |
| 98 | exc2ndOrder | Bhalla US.PLoS Comput Biol 2021 Nov 29;17(11):e1009621. / 2022-09-30 17:52:22 | Generic / | cytosol | Fit to elementary ODE model / HillTau implementation |
| 101 | baseline | Bhalla US.PLoS Comput Biol 2021 Nov 29;17(11):e1009621. / 2022-09-30 22:10:56 | Generic / | cytosol | Fit to elementary ODE model / HillTau implementation |
| 104 | fb_inhib | Bhalla US.PLoS Comput Biol 2021 Nov 29;17(11):e1009621. / 2022-09-30 22:16:21 | Generic / | cytosol | Abstract phenomenological model / HillTau implementation |
| 1 | fig2_egfr | Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication ) / 2001-11-07 00:00:00 | Generic mammalian / Brain | Surface - Nucleus | Quantitative match to experiments, Hypothetical / Exact GENESIS implementation |
| 2 | fig3_CaMKII | Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication ) / 2001-11-07 00:00:00 | Generic mammalian / Neuronal | Synapse | Quantitative match to experiments, Qualitative / Exact GENESIS implementation |
| 3 | fig4_synapse | Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication ) / 2001-11-07 00:00:00 | Generic mammalian / Neuronal | Synapse | Quantitative match to experiments, Qualitative, Hypothetical / Exact GENESIS implementation |
| 103 | gain | Bhalla US.PLoS Comput Biol 2021 Nov 29;17(11):e1009621. / 2022-09-30 22:14:44 | Generic / | cytosol | Fit to elementary ODE model / HillTau implementation |
| 73 | HomoArginine | Abu-Soud HM et al. Biochemistry. 1999 Sep 21;38(38):12446-51. ( Peer-reviewed publication ) / 2006-08-07 00:00:00 | human / Kidney cell expressing the rat brain nNOS | Cytosol | Quantitative match to experiments / Exact GENESIS implementation |
| 30 | MAPK | Huang CY and Ferrell JE Jr. Proc Natl Acad Sci U S A. (1996) 93(19):10078-83 ( peer-reviewed publication ) / 2002-01-31 00:00:00 | Xenopus / Oocytes extract | Cytosol | Quantitative match to experiments / Approximate implementation |
| 100 | inh | Bhalla US.PLoS Comput Biol 2021 Nov 29;17(11):e1009621. / 2022-09-30 22:08:48 | Generic / | cytosol | Fit to elementary ODE model / HillTau implementation |
| 66 | Pathway | Yamada S et al. FEBS Letters 2003 Jan 16;534(1-3):190-6. ( Peer-reviewed publication ) / 2006-02-13 00:00:00 | mouse / Liver | Cytosol, Nucleus | Quantitative match to experiments / Exact GENESIS implementation |
| 105 | kholodenko | Bhalla US.PLoS Comput Biol 2021 Nov 29;17(11):e1009621. / 2022-09-30 22:18:08 | Xenopus / Oocyte extract | cytosol | Fit to ODE model and experiments / HillTau implementation |
| 29 | Kierzek_LacZ | Kierzek AM. et al. J Biol Chem. (2001) 276(11):8165-72. ( peer-reviewed publication ) / 2002-01-28 00:00:00 | E. Coli / - | Internal | Qualitative / Approximate implementation |
| 18 | Kuroda_GC | Kuroda S. et al. J Neurosci. (2001) 21(15):5693-702. ( peer-reviewed publication ) / 2001-12-24 00:00:00 | Generic mammalian / Neuronal | Synapse | Quantitative match to experiments / Exact GENESIS implementation |
| 72 | L-Arginine | Abu-Soud HM et al. Biochemistry. 1999 Sep 21;38(38):12446-51. ( Peer-reviewed publication ) / 2006-08-07 00:00:00 | Human / Kidney cell expressing the rat brain nNOS | Cytosol | Quantitative match to experiments / Exact GENESIS implementation |
| 36 | luciferase | L. Yu. Brovko et al 1994, Biochemistry (Moscow) 59(2):195-201, 1994 ( peer-reviewed publication ). / 2002-12-12 00:00:00 | E. Coli / - | Cytosol | Qualitative / Approximate implementation |
| 85 | cycle | Novak B,Tyson JJ. J Theor Biol. 2004 Oct 21;230(4):563-79. ( Peer-reviewed publication ) / 2006-12-21 00:00:00 | General Mammalian / - | Nucleus | Quantitative match to experiments / Approximate implementation |
| 35 | -fig1c | Bhalla US et al. Science (2002) 297(5583):1018-23 ( peer-reviewed publication ). / 2002-11-07 00:00:00 | Generic mammalian / NIH 3T3 Expression | Surface - Nucleus | Quantitative match to experiments, Qualitative / Exact GENESIS implementation |
| 45 | adapt_fb | Asthagiri AR and Lauffenburger DA. Biotechnol Prog. (2001) 17(2):227-39. ( peer-reviewed publication ). / 2003-02-22 00:00:00 | Chinese hamster (Cricetulus griseus); mammalian / Ovary - CHO cell line | Surface, cytosol | Quantitative match to experiments, Qualitative / Mathematically equivalent |
| 46 | enz_fb | Asthagiri AR and Lauffenburger DA. Biotechnol Prog. (2001) 17(2):227-39. ( peer-reviewed publication ). / 2003-02-22 00:00:00 | Chinese hamster (Cricetulus griseus); mammalian / Ovary - CHO cell line | Surface + cytosol | Qualitative / Approximate implementation |
| 44 | no_fb | Asthagiri AR and Lauffenburger DA. Biotechnol Prog. (2001) 17(2):227-39. ( peer-reviewed publication ). / 2003-02-22 00:00:00 | Chinese hamster (Cricetulus griseus); mammalian / Ovary - CHO cell line | Surface, cytosol | Quantitative match to experiments, Qualitative / Mathematically equivalent |
| 9 | oscillation | Bhalla US, Iyengar R. Chaos (2001) 11(1):221-226. ( peer-reviewed publication ) / 2001-11-08 00:00:00 | Generic mammalian / NIH 3T3 Expression | Surface - Nucleus | Qualitative / Exact GENESIS implementation |
| 50 | 2003 | Bhalla US Biophys J. 2004 Aug;87(2):745-53. ( peer-reviewed publication ) / 2003-04-28 00:00:00 | Generic mammalian / Brain - Neuronal | Synapse | Qualitative / Exact GENESIS implementation |
| 27 | MAPK_osc | Boris N. Kholodenko Eur J Biochem. (2000) 267(6):1583-8). ( peer-reviewed publication ) / 2002-01-22 00:00:00 | Xenopus / Oocyte extract | Cytosol | Hypothetical / Mathematically equivalent |
| 4 | effects | Bhalla US et al. Science (2002) 297(5583):1018-23. ( peer-reviewed publication ) / 2001-11-07 00:00:00 | Generic mammalian / NIH 3T3 Expression | Surface - nucleus | Quantitative match to experiments / Exact GENESIS implementation |
| 102 | modifier | Bhalla US.PLoS Comput Biol 2021 Nov 29;17(11):e1009621. / 2022-09-30 22:13:03 | Generic / | cytosol | Fit to elementary ODE model / HillTau implementation |
| 94 | mRNA synthesis | Peer-reviewed publication,Book / 2014-06-10 00:00:00 | General Mammalian/Neuronal / Neuronal | Surface,Cytosol, Nucleus | Quantitative match to experiments,Approximate implementation,Qualitative,Qualitative / Approximate implementation |
| 92 | mTOR_pathway | Jain P, and Bhalla, U.S. PLoS Comput Biol. 2009 Feb;5(2). ( Peer-reviewed publication ) / 2009-02-13 00:00:00 | General Mammalian / Neuronal | Dendritic | Quantitative match to experiments / Approximate implementation |
| 74 | NMArginine | Abu-Soud HM et al. Biochemistry. 1999 Sep 21;38(38):12446-51. ( Peer-reviewed publication ) / 2006-08-07 00:00:00 | human / Kidney cell expressing the rat brain nNOS | Cytosol | Quantitative match to experiments / Exact GENESIS implementation |
| 75 | NOHArginine | Abu-Soud HM et al. Biochemistry. 1999 Sep 21;38(38):12446-51. ( Peer-reviewed publication ) / 2006-08-07 00:00:00 | human / Kidney cell expressing the rat brain nNOS | Cytosol | Quantitative match to experiments / Exact GENESIS implementation |
| 23 | IP3metabolism | Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication ) / 2002-01-07 00:00:00 | Generic mammalian / Brain - Neuronal | Cytosol | Quantitative match to experiments, Qualitative / Approximate implementation |
| 31 | IP3metabolism | Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication ) / 2002-04-03 00:00:00 | Generic mammalian / Brain - Neuronal | Cytosol | Quantitative match to experiments, Qualitative / Exact GENESIS implementation |
| 11 | NOS_Iwanaga | In-house. / 2001-11-12 00:00:00 | Rat; Mammalian / Neuronal; Expression in E.coli | Cytosol | Quantitative match to experiments / Exact GENESIS implementation |
| 20 | regulation | In-house / 2001-12-25 00:00:00 | rat; Mammalian / Brain - Neuronal; expressed in E.coli | Cytosol | Quantitative match to experiments, Qualitative / Exact GENESIS implementation |
| 111 | osc | Bhalla US. PLoS Comput Biol 2021 Nov 29;17(11):e1009621. / 2022-10-01 00:05:03 | Generic / | cytosol | Abstract phenomenological model / HillTau implementation |
| 32 | IP3metabolism | Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication ) / 2002-04-03 00:00:00 | Generic mammalian / Brain - Neuronal | Cytosol | Quantitative match to experiments, Qualitative / Exact GENESIS implementation |
| 24 | IP3metabolism | Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication ) / 2002-01-08 00:00:00 | Generic mammalian / Brain - Neuronal | Cytosol | Quantitative match to experiments, Qualitative / Approximate implementation |
| 47 | PKA_2003 | Bhalla US. (2004) Biophys J. 87(2):733-44. ( peer-reviewed publication ) / 2003-04-28 00:00:00 | Generic mammalian / Generic | Cytosol + Cell membrane | Qualitative / Exact GENESIS implementation |
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