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Accession
No.
NameSource /
Entry Date
Species /
Tissue
Cell CompartmentMethodology /
Model Implementation
108bcm_bistableBhalla US. PLoS Comput Biol 2021 Nov 29;17(11):e1009621.  /
 2022-09-30 23:49:58
Generic /
cytosolAbstract phenomenological model /
HillTau implementation
107bcmBhalla US.PLoS Comput Biol 2021 Nov 29;17(11):e1009621. /
 2022-09-30 23:36:25
Generic /
SynapseFit to ODE model and experiments /
HillTau implementation
101
  • exc_tau_
    baseline
  • Bhalla US.PLoS Comput Biol 2021 Nov 29;17(11):e1009621. /
     2022-09-30 22:10:56
    Generic /
    cytosolFit to elementary ODE model /
    HillTau implementation
    100inhBhalla US.PLoS Comput Biol 2021 Nov 29;17(11):e1009621. /
     2022-09-30 22:08:48
    Generic /
    cytosolFit to elementary ODE model /
    HillTau implementation
    99convBhalla US.PLoS Comput Biol 2021 Nov 29;17(11):e1009621. /
     2022-09-30 17:54:52
    Generic /
    cytosolFit to elementary ODE model /
    HillTau implementation
    98exc2ndOrderBhalla US.PLoS Comput Biol 2021 Nov 29;17(11):e1009621. /
     2022-09-30 17:52:22
    Generic /
    cytosolFit to elementary ODE model /
    HillTau implementation
    97excBhalla US.PLoS Comput Biol 2021 Nov 29;17(11):e1009621. /
     2022-09-30 15:13:55
    Generic /
    cytosolFit to elementary ODE model /
    HillTau implementation
    111oscBhalla US. PLoS Comput Biol 2021 Nov 29;17(11):e1009621.  /
     2022-10-01 00:05:03
    Generic /
    cytosolAbstract phenomenological model /
    HillTau implementation
    19CondorelliGCCondorelli P, George SC. Biophys J. (2001) 80(5):2110-9). ( peer-reviewed publication  /
     2001-12-25 00:00:00
    Generic mammalian /
    Pulmonary and vascular smooth muscle
    CytosolQuantitative match to experiments /
    Mathematically equivalent
    18Kuroda_GCKuroda S. et al. J Neurosci. (2001) 21(15):5693-702. ( peer-reviewed publication ) /
     2001-12-24 00:00:00
    Generic mammalian /
    Neuronal
    SynapseQuantitative match to experiments /
    Exact GENESIS implementation
    16
  • Synaptic_
    Network
  • Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication ) /
     2001-12-12 00:00:00
    Generic mammalian /
    Neuronal
    SynapseQuantitative match to experiments, Qualitative /
    Exact GENESIS implementation
    9
  • MAPK_MKP1_
    oscillation
  • Bhalla US, Iyengar R. Chaos (2001) 11(1):221-226. ( peer-reviewed publication ) /
     2001-11-08 00:00:00
    Generic mammalian /
    NIH 3T3 Expression
    Surface - NucleusQualitative /
    Exact GENESIS implementation
    12Stuehr_NOS Santolini J. et al. J Biol Chem. (2001) 276(2):1233-43. ( peer-reviewed publication ) /
     2001-11-12 00:00:00
    Generic mammalian /
    Neuronal ; Expressioned in E.coli
    CytosolQuantitative match to experiments /
    Approximate implementation
    23
  • NonOsc_Ca_
    IP3metabolism
  • Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication ) /
     2002-01-07 00:00:00
    Generic mammalian /
    Brain - Neuronal
    CytosolQuantitative match to experiments, Qualitative /
    Approximate implementation
    48PKC_2003Bhalla US. (2004) Biophys J. 87(2):733-44 .( peer-reviewed publication ) /
     2003-04-28 00:00:00
    Generic mammalian /
    Generic
    Cytosol + Cell membraneQualitative /
    Exact GENESIS implementation
    83d_fold_modelBhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication ) /
     2001-11-08 00:00:00
    Generic mammalian /
    NIH 3T3 Expression
    Surface - NucleusQuantitative match to experiments /
    Exact GENESIS implementation
    33CaMKIIWilliam R. Holmes J Comput Neurosci. (2000) 8(1):65-85 ( peer-reviewed publication ) /
     2002-08-21 00:00:00
    Generic mammalian /
    Brain - Neuronal
    SynapseQualitative /
    Approximate implementation
    49CaMKII_2003Bhalla US. Biophys J. 2004 Aug;87(2):733-44. ( peer-reviewed publication ). /
     2003-04-28 00:00:00
    Generic mammalian /
    Brain - Neuronal
    SynapseQualitative /
    Exact GENESIS implementation
    50
  • MAPK_network_
    2003
  • Bhalla US Biophys J. 2004 Aug;87(2):745-53. ( peer-reviewed publication ) /
     2003-04-28 00:00:00
    Generic mammalian /
    Brain - Neuronal
    SynapseQualitative /
    Exact GENESIS implementation
    47PKA_2003Bhalla US. (2004) Biophys J. 87(2):733-44. ( peer-reviewed publication ) /
     2003-04-28 00:00:00
    Generic mammalian /
    Generic
    Cytosol + Cell membraneQualitative /
    Exact GENESIS implementation
    2fig3_CaMKIIBhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication ) /
     2001-11-07 00:00:00
    Generic mammalian /
    Neuronal
    SynapseQuantitative match to experiments, Qualitative /
    Exact GENESIS implementation
    58EGFR_MAPKBhalla US. Biophys J. (2004) 87(2):745-53. ( peer-reviewed publication ) /
     2004-01-14 00:00:00
    Generic mammalian /
    Neuronal
    SynapseQualitative /
    Exact GENESIS implementation
    3fig4_synapseBhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication ) /
     2001-11-07 00:00:00
    Generic mammalian /
    Neuronal
    SynapseQuantitative match to experiments, Qualitative, Hypothetical /
    Exact GENESIS implementation
    35
  • MAPK-bistability
    -fig1c
  • Bhalla US et al. Science (2002) 297(5583):1018-23 ( peer-reviewed publication ). /
     2002-11-07 00:00:00
    Generic mammalian /
    NIH 3T3 Expression
    Surface - NucleusQuantitative match to experiments, Qualitative /
    Exact GENESIS implementation
    4
  • mkp1_feedback_
    effects
  • Bhalla US et al. Science (2002) 297(5583):1018-23. ( peer-reviewed publication ) /
     2001-11-07 00:00:00
    Generic mammalian /
    NIH 3T3 Expression
    Surface - nucleusQuantitative match to experiments /
    Exact GENESIS implementation
    32
  • Osc_Ca_
    IP3metabolism
  • Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication ) /
     2002-04-03 00:00:00
    Generic mammalian /
    Brain - Neuronal
    CytosolQuantitative match to experiments, Qualitative /
    Exact GENESIS implementation
    31
  • NonOsc_Ca_
    IP3metabolism
  • Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication ) /
     2002-04-03 00:00:00
    Generic mammalian /
    Brain - Neuronal
    CytosolQuantitative match to experiments, Qualitative /
    Exact GENESIS implementation
    1fig2_egfrBhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication ) /
     2001-11-07 00:00:00
    Generic mammalian /
    Brain
    Surface - NucleusQuantitative match to experiments, Hypothetical /
    Exact GENESIS implementation
    26PKC_turnoverIn-house  /
     2002-01-22 00:00:00
    Generic mammalian /
    Brain - Neuronal
    Cell membrane +CytosolQuantitative match to experiments, Qualitative /
    Exact GENESIS implementation
    25cAMP_pathwayBhalla US Methods Enzymol. 2002;345:3-23). ( peer-reviewed publication ) /
     2002-01-12 00:00:00
    Generic mammalian /
    Brain - Neuronal
    Cell membrane + CytosolQuantitative match to experiments, Qualitative /
    Exact GENESIS implementation
    24
  • Osc_Ca_
    IP3metabolism
  • Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication ) /
     2002-01-08 00:00:00
    Generic mammalian /
    Brain - Neuronal
    CytosolQuantitative match to experiments, Qualitative /
    Approximate implementation
    52
  • EGFR_Signaling_
    pathway
  • Quantification of Short Term Signaling by the EGFR Kholodenko et al, The J Biol Chem. , Vol 274, No. 42, Issue of October 15, pp. 30169 - 30181, 1999. ( peer-reviewed publication ) /
     2003-05-17 00:00:00
    Harlan Sprague Dawley rat; mammalian /
    Hepatocytes
    Cell membrane + cytosolQualitative /
    Mathematically equivalent
    74NMArginineAbu-Soud HM et al. Biochemistry. 1999 Sep 21;38(38):12446-51. ( Peer-reviewed publication ) /
     2006-08-07 00:00:00
    human /
    Kidney cell expressing the rat brain nNOS
    CytosolQuantitative match to experiments /
    Exact GENESIS implementation
    75NOHArginineAbu-Soud HM et al. Biochemistry. 1999 Sep 21;38(38):12446-51. ( Peer-reviewed publication ) /
     2006-08-07 00:00:00
    human /
    Kidney cell expressing the rat brain nNOS
    CytosolQuantitative match to experiments /
    Exact GENESIS implementation
    73HomoArginineAbu-Soud HM et al. Biochemistry. 1999 Sep 21;38(38):12446-51. ( Peer-reviewed publication ) /
     2006-08-07 00:00:00
    human /
    Kidney cell expressing the rat brain nNOS
    CytosolQuantitative match to experiments /
    Exact GENESIS implementation
    72L-ArginineAbu-Soud HM et al. Biochemistry. 1999 Sep 21;38(38):12446-51. ( Peer-reviewed publication ) /
     2006-08-07 00:00:00
    Human /
    Kidney cell expressing the rat brain nNOS
    CytosolQuantitative match to experiments /
    Exact GENESIS implementation
    42
  • CDK2-CyclinA_
    activation_
    pathway
  • Morris MC. et al. J Biol Chem. (2002) 277(26):23847-53. ( peer-reviewed publication ) /
     2003-01-11 00:00:00
    Human, Xenopus /
    Expressed in E.coli
    CytosolQualitative /
    Exact GENESIS implementation
    43
  • CDK2-CyclinA_
    activation_
    improved
  • Morris MC. et al. J Biol Chem. (2002) 277(26):23847-53. ( peer-reviewed publication ) /
     2003-01-11 00:00:00
    Human, Xenopus /
    Expressed in E.coli
    CytosolQuantitative match to experiments /
    Exact GENESIS implementation
    66
  • Jak-Stat_
    Pathway
  • Yamada S et al. FEBS Letters 2003 Jan 16;534(1-3):190-6. ( Peer-reviewed publication ) /
     2006-02-13 00:00:00
    mouse /
    Liver
    Cytosol, NucleusQuantitative match to experiments /
    Exact GENESIS implementation
    67SOCS1_knockoutYamada S et al. FEBS Letters 2003 Jan 16;534(1-3):190-6. ( Peer-reviewed publication ) /
     2006-02-13 00:00:00
    mouse /
    Liver
    Nucleus , cytoplasmQuantitative match to experiments /
    Exact GENESIS implementation