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Accession Type:
Network
AMPAR_CaMKII_
weak_coupling
Shared_Object_
AMPAR_CaMKII_
weak_coupling
CaMKII
 Molecule
 Enzyme
 Reaction
CaM
PP1
PP2B
PP1_PSD
AMPAR
PKA
AC
AMPAR_memb
PP1_CaMKII_PSD
CaMKII_PSD

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Parameters for CaMKII (Pathway Number 282)

Pathway Layout

Pathway Basic Parameters

Pathway NameCaMKII
Pathway Entry Number 282
Accession Number 65
Accession Name AMPAR_CaMKII_weak_coupling
Species General Mammalian
Tissue Neuronal
CellCompartmentSynaptic Spine, Postsynaptic Density
Related Pathways 13, 26, 80, 106, 121, 145, 159, 174, 202, 216, 235, 245, 258, 264, 272, 322, 339, 357
Notes Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzs look a terrible mess. Actually it is just 3 reactions for diff sites, by 4 states of CaMKII, defined by the phosph state.

Statistics

11
4
2

Conversion format

This pathway is part of accession 65 and is completely specified in the file acc65.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc65.g   
MATLAB format    acc65.m   
SBML format    acc65.xml   


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Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR
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