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Parameters for PKA (Pathway Number 84)
Pathway Basic Parameters
| Pathway Name||PKA|
| Pathway Entry Number || 84|
| Accession Number ||16|
| Accession Name ||Synaptic_Network|
| Species ||Generic mammalian|
| Tissue ||Neuronal|
| Related Pathways ||17,
| Notes|| Protein kinase A. It has two regulatory and two catalytic subunits, represented here as R2C2. Each regulatory subunit binds two cAMPs. I also model an inhibitor of PKA which binds stoichiometrically and thus sharpens the response curve for PKA against cAMP. General reference: Taylor et al Ann Rev Biochem 1990 59:971-1005 Other references Ogreid and Doskeland 1983 Biochem 22:1686-1696 is a great, detailed paper. Also: Ogreid and Doskeland 1982 FEBS Lett 150(1):161-166 Ogreid et al 1983 JBC 258(2):1041-1049 Robinson-Steiner and Corbin 1983 JBC 258(2):1032-1040 Hasler et al 1992 FASEB J 6:2735-2741
|This pathway is part of accession 16 and is completely specified in the file acc16.g.|
There is no separate files for just this pathway.
|Native Format (GENESIS format)|| acc16.g |
|GENESIS Format (Annotated version)|| Anno_acc16.g |
Pathway Detail Molecule List Enzyme List Reaction List
|Database compilation and code copyright (C) 2005, Upinder S. Bhalla and NCBS/TIFR |
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