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Result: 1 - 20 of 34 rows are displayed Previous of 2  Next

Pathway List for CamKII

Default ordering is done according to Pathway Name.Table header can be used for changing the default ordering.
indicates that ordering is done according to ascending or descending order.
Entries are color tagged depending on Network  or Pathway 
#2#2#3#3#3#1#1#19#19#19#19#19#1#19#19#19#1#19#19#19
  Pathway Name
Pathway No.		Accession Name
Accession No.		Accession
Type		Pathway statisticsCamKII statisticsSource
Entry Date
1 CaMKII_g
Pathway No. 1138		 bcm

Accession No. 107		PathwayMolecule = 2
Enzyme   = 0
Reaction  = 0
Molecule = 2
Enzyme   = 0
Reaction  = 0
Bhalla US.PLoS Comput Biol 2021 Nov 29;17(11):e1009621./
2022-09-30 23:36:25
   Related Pathway: 
1142
    This model was used to generate Fig 3 C, D ,E, Fig 6,Fig7 supp C in Bhalla US. HillTau: A fast, compact abstraction for model reduction in biochemical signaling networks. PLoS Comput Biol 2021 Nov 29;17(11):e1009621.
   
This pathway is part of accession 107 and is completely specified in the file acc107.g.
There is no separate file for just this pathway.
FormatFile
HillTau format    acc107.json   
2 CaMKII_g
Pathway No. 1142		 bcm_bistable

Accession No. 108		PathwayMolecule = 4
Enzyme   = 0
Reaction  = 0
Molecule = 3
Enzyme   = 0
Reaction  = 0
Bhalla US. PLoS Comput Biol 2021 Nov 29;17(11):e1009621. /
2022-09-30 23:49:58
   Related Pathway: 
1138
    This model was used to generate Fig 3 G in Bhalla US. HillTau: A fast, compact abstraction for model reduction in biochemical signaling networks. PLoS Comput Biol 2021 Nov 29;17(11):e1009621.
   
This pathway is part of accession 108 and is completely specified in the file acc108.g.
There is no separate file for just this pathway.
FormatFile
HillTau format    acc108.json   
3 CaMKIII_g
Pathway No. 1145		 syn_prot_
composite
Accession No. 109		PathwayMolecule = 2
Enzyme   = 0
Reaction  = 0
Molecule = 2
Enzyme   = 0
Reaction  = 0
Bhalla US. PLoS Comput Biol 2021 Nov 29;17(11):e1009621. /
2022-09-30 23:58:38
   Related Pathway: 
1151, 1159
    This model was used to generate fig 5 D to k, fig 6 in Bhalla US. HillTau: A fast, compact abstraction for model reduction in biochemical signaling networks. PLoS Comput Biol 2021 Nov 29;17(11):e1009621.
   
This pathway is part of accession 109 and is completely specified in the file acc109.g.
There is no separate file for just this pathway.
FormatFile
HillTau format    acc109.json   
4 CaMKIII_g
Pathway No. 1151		 aut6

Accession No. 110		PathwayMolecule = 3
Enzyme   = 0
Reaction  = 0
Molecule = 3
Enzyme   = 0
Reaction  = 0
Bhalla US. PLoS Comput Biol 2021 Nov 29;17(11):e1009621. /
2022-10-01 00:02:13
   Related Pathway: 
1145, 1159
    This model was used to generate Fig 6 in Bhalla US. HillTau: A fast, compact abstraction for model reduction in biochemical signaling networks. PLoS Comput Biol 2021 Nov 29;17(11):e1009621.
   
This pathway is part of accession 110 and is completely specified in the file acc110.g.
There is no separate file for just this pathway.
FormatFile
HillTau format    acc110.json   
5 CaMKIII_g
Pathway No. 1159		 syn_CaMKIII

Accession No. 114		PathwayMolecule = 2
Enzyme   = 0
Reaction  = 0
Molecule = 2
Enzyme   = 0
Reaction  = 0
Bhalla US. PLoS Comput Biol 2021 Nov 29;17(11):e1009621. /
2022-10-01 00:12:23
   Related Pathway: 
1145, 1151
    This model was used to generate Fig 3 supp A to F in Bhalla US. HillTau: A fast, compact abstraction for model reduction in biochemical signaling networks. PLoS Comput Biol 2021 Nov 29;17(11):e1009621.
   
This pathway is part of accession 114 and is completely specified in the file acc114.g.
There is no separate file for just this pathway.
FormatFile
HillTau format    acc114.json   
6 
  • Shared_Object_
    CaMKIII
    Pathway No. 1093
    		•  CaMKIII

    Accession No. 90    		NetworkMolecule = 15
    Enzyme   = 5
    Reaction  = 3
    		Molecule = 4
    Enzyme   = 4
    Reaction  = 2
    		Jain P, and Bhalla, U.S. PLoS Comput Biol. 2009 Feb;5(2). ( Peer-reviewed publication )/
    2009-02-12 00:00:00
       Related Pathway: ------
        CaMKIII is activated by Ca2+ and inactivated by S6K. Since CaMKIII inhibits eEF2, the net effect of Ca2+ on elongation is inhibitory and of S6K is excitatory
       
    This pathway is part of accession 90 and is completely specified in the file acc90.g.
    There is no separate file for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc90.g   
    7 
  • Shared_Object_
    fig3_CaMKII
    Pathway No. 12
    		•  fig3_CaMKII

    Accession No. 2    		NetworkMolecule = 15
    Enzyme   = 16
    Reaction  = 0
    		Molecule = 1
    Enzyme   = 0
    Reaction  = 0
    		Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/
    2001-11-07 00:00:00
       Related Pathway: ------
        This is the model file for figure 3 from Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It is a model of the Ca activation of CaMKII and other CaM-activated enzymes. It includes the regulatory phosphatases PP1 and PP2B (Calcineurin) acting on CaMKII and also includes CaM-activated adenylyl cyclase and PKA in the synapse.
    Demonstration script files for generating the figures in the paper, including figure 3, are available here.
       
    This pathway is part of accession 2 and is completely specified in the file acc2.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc2.g   
    GENESIS Format (Annotated version)    Anno_acc2.g   
    8 CaMKII
    Pathway No. 13    		 fig3_CaMKII

    Accession No. 2    		NetworkMolecule = 9
    Enzyme   = 4
    Reaction  = 3
    		Molecule = 8
    Enzyme   = 4
    Reaction  = 1
    		Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/
    2001-11-07 00:00:00
       Related Pathway: 
    26, 80, 106, 121, 145, 159, 174, 202, 216, 235, 245, 258, 264, 272, 282, 322, 339, 357
        This is the model file for figure 3 from Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It is a model of the Ca activation of CaMKII and other CaM-activated enzymes. It includes the regulatory phosphatases PP1 and PP2B (Calcineurin) acting on CaMKII and also includes CaM-activated adenylyl cyclase and PKA in the synapse.
    Demonstration script files for generating the figures in the paper, including figure 3, are available here.
       
    This pathway is part of accession 2 and is completely specified in the file acc2.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc2.g   
    GENESIS Format (Annotated version)    Anno_acc2.g   
    9 CaMKII
    Pathway No. 26    		 fig4_synapse

    Accession No. 3    		NetworkMolecule = 9
    Enzyme   = 4
    Reaction  = 3
    		Molecule = 8
    Enzyme   = 4
    Reaction  = 1
    		Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/
    2001-11-07 00:00:00
       Related Pathway: 
    13, 80, 106, 121, 145, 159, 174, 202, 216, 235, 245, 258, 264, 272, 282, 322, 339, 357
        This is the composite model of 4 kinases: PKC, MAPK, PKA and CaMKII and numerous regulatory pathways involved in synaptic signaling. From Bhalla US and Iyengar R. Science (1999) 283(5400):381-7.This model comes from figure 4 of that paper.
    Demonstration script files for generating the figures in the paper, including figure 4, are available here.
       
    This pathway is part of accession 3 and is completely specified in the file acc3.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc3.g   
    GENESIS Format (Annotated version)    Anno_acc3.g   
    10 CaMKII
    Pathway No. 322    		 Ajay_Bhalla_
    2004_PKM_Tuning
    Accession No. 76    		NetworkMolecule = 8
    Enzyme   = 4
    Reaction  = 3
    		Molecule = 7
    Enzyme   = 4
    Reaction  = 1
    		Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. ( Peer-reviewed publication )/
    2006-12-12 00:00:00
       Related Pathway: 
    13, 26, 80, 106, 121, 145, 159, 174, 202, 216, 235, 245, 258, 264, 272, 282, 339, 357
        Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzs look a terrible mess. Actually it is just 3 reactions for diff sites, by 4 states of CaMKII, defined by the phosph state.
       
    This pathway is part of accession 76 and is completely specified in the file acc76.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc76.g   
    MATLAB format    acc76.m   
    SBML format    acc76.xml   
    11 CaMKII
    Pathway No. 357    		 Ajay_Bhalla_
    2004_Feedback_
    Tuning
    Accession No. 78    		NetworkMolecule = 8
    Enzyme   = 4
    Reaction  = 3
    		Molecule = 7
    Enzyme   = 4
    Reaction  = 1
    		Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. ( Peer-reviewed publication )/
    2006-12-12 00:00:00
       Related Pathway: 
    13, 26, 80, 106, 121, 145, 159, 174, 202, 216, 235, 245, 258, 264, 272, 282, 322, 339
        Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzs look a terrible mess. Actually it is just 3 reactions for diff sites, by 4 states of CaMKII, defined by the phosph state.
       
    This pathway is part of accession 78 and is completely specified in the file acc78.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc78.g   
    MATLAB format    acc78.m   
    SBML format    acc78.xml   
    12 CaMKII
    Pathway No. 339    		 Ajay_Bhalla_
    2004_PKM_MKP3_
    Tuning
    Accession No. 77    		NetworkMolecule = 8
    Enzyme   = 4
    Reaction  = 3
    		Molecule = 7
    Enzyme   = 4
    Reaction  = 1
    		Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80 ( Peer-reviewed publication )/
    2006-12-12 00:00:00
       Related Pathway: 
    13, 26, 80, 106, 121, 145, 159, 174, 202, 216, 235, 245, 258, 264, 272, 282, 322, 357
        Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzs look a terrible mess. Actually it is just 3 reactions for diff sites, by 4 states of CaMKII, defined by the phosph state.
       
    This pathway is part of accession 77 and is completely specified in the file acc77.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc77.g   
    MATLAB format    acc77.m   
    SBML format    acc77.xml   
    13 
  • Shared_Object_
    CaMKII
    Pathway No. 172
    		•  CaMKII

    Accession No. 33    		NetworkMolecule = 1
    Enzyme   = 0
    Reaction  = 0
    		Molecule = 0
    Enzyme   = 0
    Reaction  = 0
    		William R. Holmes J Comput Neurosci. (2000) 8(1):65-85 ( peer-reviewed publication )/
    2002-08-21 00:00:00
       Related Pathway: ------
        This is a deterministic, point kinetics approximation to the dendritic spine CaMKII model described in William R. Holmes J Comput Neurosci. (2000) 8(1):65-85. Rates are the same but the responses differ somewhat because this model does not include the stochastic and diffusive calculations of the original.
       
    This pathway is part of accession 33 and is completely specified in the file acc33.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc33.g   
    GENESIS Format (Annotated version)    Anno_acc33.g   
    14 CaMKII
    Pathway No. 174    		 CaMKII

    Accession No. 33    		NetworkMolecule = 11
    Enzyme   = 2
    Reaction  = 14
    		Molecule = 8
    Enzyme   = 2
    Reaction  = 9
    		William R. Holmes J Comput Neurosci. (2000) 8(1):65-85 ( peer-reviewed publication )/
    2002-08-21 00:00:00
       Related Pathway: 
    13, 26, 80, 106, 121, 145, 159, 202, 216, 235, 245, 258, 264, 272, 282, 322, 339, 357
        This is a deterministic, point kinetics approximation to the dendritic spine CaMKII model described in William R. Holmes J Comput Neurosci. (2000) 8(1):65-85. Rates are the same but the responses differ somewhat because this model does not include the stochastic and diffusive calculations of the original.
       
    FormatFile
    Native Format (GENESIS format)    path174.g   
    GENESIS Format (Annotated version)    Anno_path174.g   
    15 CaMKII
    Pathway No. 80    		 Synaptic_
    Network
    Accession No. 16    		NetworkMolecule = 9
    Enzyme   = 4
    Reaction  = 3
    		Molecule = 8
    Enzyme   = 4
    Reaction  = 1
    		Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/
    2001-12-12 00:00:00
       Related Pathway: 
    13, 26, 106, 121, 145, 159, 174, 202, 216, 235, 245, 258, 264, 272, 282, 322, 339, 357
        Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzymes look a bit complicated. Actually it is just 3 reactions for different sites, by 4 states of CaMKII, defined by the phosphorylation state. This model approximates the fact that the enzyme is actually present as a decamer/dodecamer. It does so by treating the autophosphorylation reactions as being independent of the concentration of CaMKII. Also the rates for the autophosphorylation steps have been scaled to fit this approximation.
       
    This pathway is part of accession 16 and is completely specified in the file acc16.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc16.g   
    GENESIS Format (Annotated version)    Anno_acc16.g   
    16 CaMKII
    Pathway No. 216    		 MAPK_network_
    2003
    Accession No. 50    		NetworkMolecule = 8
    Enzyme   = 4
    Reaction  = 3
    		Molecule = 7
    Enzyme   = 4
    Reaction  = 1
    		Bhalla US Biophys J. 2004 Aug;87(2):745-53. ( peer-reviewed publication )/
    2003-04-28 00:00:00
       Related Pathway: 
    13, 26, 80, 106, 121, 145, 159, 174, 202, 235, 245, 258, 264, 272, 282, 322, 339, 357
        Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzs look a terrible mess. Actually it is just 3 reactions for diff sites, by 4 states of CaMKII, defined by the phosph state.
       
    FormatFile
    Native Format (GENESIS format)    path216.g   
    GENESIS Format (Annotated version)    Anno_path216.g   
    MATLAB format    path216.m   
    17 
  • Shared_Object_
    CaMKII_2003
    Pathway No. 201
    		•  CaMKII_2003

    Accession No. 49    		NetworkMolecule = 10
    Enzyme   = 14
    Reaction  = 0
    		Molecule = 0
    Enzyme   = 0
    Reaction  = 0
    		Bhalla US. Biophys J. 2004 Aug;87(2):733-44. ( peer-reviewed publication )./
    2003-04-28 00:00:00
       Related Pathway: ------
        Based on nonscaf_syn1.g. Stripped out everything except stuff which directly controls CaMKII. Designed to do doser of CaMKII vs Ca.
       
    This pathway is part of accession 49 and is completely specified in the file acc49.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc49.g   
    GENESIS Format (Annotated version)    Anno_acc49.g   
    MATLAB format    acc49.m   
    SBML format    acc49.xml   
    18 CaMKII
    Pathway No. 202    		 CaMKII_2003

    Accession No. 49    		NetworkMolecule = 8
    Enzyme   = 4
    Reaction  = 3
    		Molecule = 7
    Enzyme   = 4
    Reaction  = 1
    		Bhalla US. Biophys J. 2004 Aug;87(2):733-44. ( peer-reviewed publication )./
    2003-04-28 00:00:00
       Related Pathway: 
    13, 26, 80, 106, 121, 145, 159, 174, 216, 235, 245, 258, 264, 272, 282, 322, 339, 357
        Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzs look a terrible mess. Actually it is just 3 reactions for diff sites, by 4 states of CaMKII, defined by the phosph state.
       
    This pathway is part of accession 49 and is completely specified in the file acc49.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc49.g   
    GENESIS Format (Annotated version)    Anno_acc49.g   
    MATLAB format    acc49.m   
    SBML format    acc49.xml   
    19 CaMKII
    Pathway No. 106    		 NonOsc_Ca_
    IP3metabolism
    Accession No. 23    		NetworkMolecule = 10
    Enzyme   = 13
    Reaction  = 3
    		Molecule = 8
    Enzyme   = 8
    Reaction  = 1
    		 Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication )/
    2002-01-07 00:00:00
       Related Pathway: 
    13, 26, 80, 121, 145, 159, 174, 202, 216, 235, 245, 258, 264, 272, 282, 322, 339, 357
        Main reference here is the review by Hanson PI, Schulman H. Annu Rev Biochem. 1992;61:559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson PI, Schulman H. J Biol Chem. 1992 Aug 25;267(24):17216-24. The enzymes look a bit complicated. Actually it is just 3 reactions for different sites, by 4 states of CaMKII, defined by the phosphorylation state. This model approximates the fact that the enzyme is actually present as a decamer/dodecamer. It does so by treating the autophosphorylation reactions as being independent of the concentration of CaMKII. Also the rates for the autophosphorylation steps have been scaled to fit this approximation.
       
    This pathway is part of accession 23 and is completely specified in the file acc23.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc23.g   
    GENESIS Format (Annotated version)    Anno_acc23.g   
    20 CaMKII
    Pathway No. 121    		 Osc_Ca_
    IP3metabolism
    Accession No. 24    		NetworkMolecule = 10
    Enzyme   = 13
    Reaction  = 3
    		Molecule = 8
    Enzyme   = 8
    Reaction  = 1
    		 Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication )/
    2002-01-08 00:00:00
       Related Pathway: 
    13, 26, 80, 106, 145, 159, 174, 202, 216, 235, 245, 258, 264, 272, 282, 322, 339, 357
        Main reference here is the review by Hanson and Schulman, Ann Rev Biochem 1992 vol 61 pp 559-601. Most of the mechanistic details and a few constants are derived from there. Many kinetics are from Hanson and Schulman JBC 267:24 17216-17224 1992. The enzymes look a bit complicated. Actually it is just 3 reactions for different sites, by 4 states of CaMKII, defined by the phosphorylation state. This model approximates the fact that the enzyme is actually present as a decamer/dodecamer. It does so by treating the autophosphorylation reactions as being independent of the concentration of CaMKII. Also the rates for the autophosphorylation steps have been scaled to fit this approximation.
       
    This pathway is part of accession 24 and is completely specified in the file acc24.g.
    There is no separate files for just this pathway.
    FormatFile
    Native Format (GENESIS format)    acc24.g   
    GENESIS Format (Annotated version)    Anno_acc24.g   
     
    Result: 1 - 20 of 34 rows are displayed Previous of 2  Next


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