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Default ordering is done according to Pathway Name.Table header can be used for changing the default ordering. indicates that ordering is done according to ascending or descending order.Entries are color tagged depending on Network or Pathway ![]() |
Pathway Name![]() Pathway No. | Accession Name Accession No. | Accession Type | Pathway statistics | gq statistics | Source Entry Date | ||||||||||||||
| 1 | Gq Pathway No. 5 | fig2_egfr Accession No. 1 | Network | Molecule = 7 Enzyme = 0 Reaction = 9 | Molecule = 0 Enzyme = 0 Reaction = 0 | Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/ 2001-11-07 00:00:00 | |||||||||||||
| Related Pathway: 23, 74, 111, 125, 150, 163, 210, 316, 334, 351 | |||||||||||||||||||
| This network was used to generate figure 2 in Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It consists of the MAPK cascade in a feedback loop with PKC, and receives input from the EGFR in the synapse. Demonstration script files for generating the figures in the paper, including figure 2, are available here. | |||||||||||||||||||
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| 2 | Gq Pathway No. 23 | fig4_synapse Accession No. 3 | Network | Molecule = 7 Enzyme = 0 Reaction = 9 | Molecule = 0 Enzyme = 0 Reaction = 0 | Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/ 2001-11-07 00:00:00 | |||||||||||||
| Related Pathway: 5, 74, 111, 125, 150, 163, 210, 316, 334, 351 | |||||||||||||||||||
| This is the composite model of 4 kinases: PKC, MAPK, PKA and CaMKII and numerous regulatory pathways involved in synaptic signaling. From Bhalla US and Iyengar R. Science (1999) 283(5400):381-7.This model comes from figure 4 of that paper. Demonstration script files for generating the figures in the paper, including figure 4, are available here. | |||||||||||||||||||
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| 3 | Gq Pathway No. 74 | Synaptic_ Network Accession No. 16 | Network | Molecule = 7 Enzyme = 0 Reaction = 9 | Molecule = 0 Enzyme = 0 Reaction = 0 | Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/ 2001-12-12 00:00:00 | |||||||||||||
| Related Pathway: 5, 23, 111, 125, 150, 163, 210, 316, 334, 351 | |||||||||||||||||||
| The model for the Gq pathway plus its activators, here represented by the metabotropic glutamate receptor. We assume GTP is present in fixed amounts, so we leave it out of the explicit equations in this model. Normally we would expect it to associate along with the G-Receptor-ligand complex. Most info is from Berstein et al JBC 267:12 8081-8088 1992 Structure of receptor activation of Gq from Fay et al Biochem 30 5066-5075 1991 This mGluR/Gq model lacks a mechanism for receptor desensitization. | |||||||||||||||||||
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| 4 | Gq Pathway No. 111 | NonOsc_Ca_ IP3metabolism Accession No. 23 | Network | Molecule = 11 Enzyme = 0 Reaction = 9 | Molecule = 0 Enzyme = 0 Reaction = 0 | Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication )/ 2002-01-07 00:00:00 | |||||||||||||
| Related Pathway: 5, 23, 74, 125, 150, 163, 210, 316, 334, 351 | |||||||||||||||||||
| The model for the Gq pathway plus its activators, here represented by the metabotropic glutamate receptor. We assume GTP is present in fixed amounts, so we leave it out of the explicit equations in this model. Normally we would expect it to associate along with the G-Receptor-ligand complex. Most info is from Berstein G et al J Biol Chem. 1992 Apr 25;267(12):8081-8. Structure of receptor activation of Gq from Fay SP et al Biochemistry. 1991 May 21;30(20):5066-75.This mGluR/Gq model lacks a mechanism for receptor desensitization. | |||||||||||||||||||
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| 5 | Gq Pathway No. 125 | Osc_Ca_ IP3metabolism Accession No. 24 | Network | Molecule = 11 Enzyme = 0 Reaction = 9 | Molecule = 0 Enzyme = 0 Reaction = 0 | Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication )/ 2002-01-08 00:00:00 | |||||||||||||
| Related Pathway: 5, 23, 74, 111, 150, 163, 210, 316, 334, 351 | |||||||||||||||||||
| The model for the Gq pathway plus its activators, here represented by the metabotropic glutamate receptor. We assume GTP is present in fixed amounts, so we leave it out of the explicit equations in this model. Normally we would expect it to associate along with the G-Receptor-ligand complex. Most info is from Berstein et al JBC 267:12 8081-8088 1992 Structure of receptor activation of Gq from Fay et al Biochem 30 5066-5075 1991 This mGluR/Gq model lacks a mechanism for receptor desensitization. | |||||||||||||||||||
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| 6 | Gq Pathway No. 150 | NonOsc_Ca_ IP3metabolism Accession No. 31 | Network | Molecule = 11 Enzyme = 0 Reaction = 9 | Molecule = 0 Enzyme = 0 Reaction = 0 | Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication )/ 2002-04-03 00:00:00 | |||||||||||||
| Related Pathway: 5, 23, 74, 111, 125, 163, 210, 316, 334, 351 | |||||||||||||||||||
| The model for the Gq pathway plus its activators, here represented by the metabotropic glutamate receptor. We assume GTP is present in fixed amounts, so we leave it out of the explicit equations in this model. Normally we would expect it to associate along with the G-Receptor-ligand complex. Most info is from Berstein et al JBC 267:12 8081-8088 1992 Structure of receptor activation of Gq from Fay et al Biochem 30 5066-5075 1991 This mGluR/Gq model lacks a mechanism for receptor desensitization. | |||||||||||||||||||
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| 7 | Gq Pathway No. 163 | Osc_Ca_ IP3metabolism Accession No. 32 | Network | Molecule = 11 Enzyme = 0 Reaction = 9 | Molecule = 0 Enzyme = 0 Reaction = 0 | Mishra J, Bhalla US. Biophys J. 2002 Sep;83(3):1298-316. ( peer-reviewed publication )/ 2002-04-03 00:00:00 | |||||||||||||
| Related Pathway: 5, 23, 74, 111, 125, 150, 210, 316, 334, 351 | |||||||||||||||||||
| The model for the Gq pathway plus its activators, here represented by the metabotropic glutamate recept or. We assume GTP is present in fixed amounts, so we leave it out of the explicit equations in this model. Normal ly we would expect it to associate along with the G-Receptor-ligand complex. Most info is from Berstein et al JB C 267:12 8081-8088 1992 Structure of receptor activation of Gq from Fay et al Biochem 30 5066-5075 1991 This mGl uR/Gq model lacks a mechanism for receptor desensitization. | |||||||||||||||||||
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| 8 | Gq Pathway No. 210 | MAPK_network_ 2003 Accession No. 50 | Network | Molecule = 7 Enzyme = 0 Reaction = 9 | Molecule = 0 Enzyme = 0 Reaction = 0 | Bhalla US Biophys J. 2004 Aug;87(2):745-53. ( peer-reviewed publication )/ 2003-04-28 00:00:00 | |||||||||||||
| Related Pathway: 5, 23, 74, 111, 125, 150, 163, 316, 334, 351 | |||||||||||||||||||
| We assume GTP is present in fixed amounts, so we leave it out of the explicit equations in this model. Normally we would expect it to associate along with the G-Receptor-ligand complex. Most info is from Berstein et al JBC 267:12 8081-8088 1992 Structure of rec activation of Gq from Fay et al Biochem 30 5066-5075 1991 | |||||||||||||||||||
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| 9 | Gq Pathway No. 316 | Ajay_Bhalla_ 2004_PKM_Tuning Accession No. 76 | Network | Molecule = 7 Enzyme = 0 Reaction = 9 | Molecule = 0 Enzyme = 0 Reaction = 0 | Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. ( Peer-reviewed publication )/ 2006-12-12 00:00:00 | |||||||||||||
| Related Pathway: 5, 23, 74, 111, 125, 150, 163, 210, 334, 351 | |||||||||||||||||||
| We assume GTP is present in fixed amounts, so we leave it out of the explicit equations in this model. Normally we would expect it to associate along with the G-Receptor-ligand complex. Most info is from Berstein et al JBC 267:12 8081-8088 1992 Structure of rec activation of Gq from Fay et al Biochem 30 5066-5075 1991 | |||||||||||||||||||
| 10 | Gq Pathway No. 334 | Ajay_Bhalla_ 2004_PKM_MKP3_ Tuning Accession No. 77 | Network | Molecule = 7 Enzyme = 0 Reaction = 9 | Molecule = 0 Enzyme = 0 Reaction = 0 | Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80 ( Peer-reviewed publication )/ 2006-12-12 00:00:00 | |||||||||||||
| Related Pathway: 5, 23, 74, 111, 125, 150, 163, 210, 316, 351 | |||||||||||||||||||
| We assume GTP is present in fixed amounts, so we leave it out of the explicit equations in this model. Normally we would expect it to associate along with the G-Receptor-ligand complex. Most info is from Berstein et al JBC 267:12 8081-8088 1992 Structure of rec activation of Gq from Fay et al Biochem 30 5066-5075 1991 | |||||||||||||||||||
| 11 | Gq Pathway No. 351 | Ajay_Bhalla_ 2004_Feedback_ Tuning Accession No. 78 | Network | Molecule = 7 Enzyme = 0 Reaction = 9 | Molecule = 0 Enzyme = 0 Reaction = 0 | Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. ( Peer-reviewed publication )/ 2006-12-12 00:00:00 | |||||||||||||
| Related Pathway: 5, 23, 74, 111, 125, 150, 163, 210, 316, 334 | |||||||||||||||||||
| We assume GTP is present in fixed amounts, so we leave it out of the explicit equations in this model. Normally we would expect it to associate along with the G-Receptor-ligand complex. Most info is from Berstein et al JBC 267:12 8081-8088 1992 Structure of rec activation of Gq from Fay et al Biochem 30 5066-5075 1991 | |||||||||||||||||||
indicates that ordering is done according to ascending or descending order.
or Pathway 