DOQCS database

NCBS Home page

Accession List

Pathway List

Authorized Users

Help

News archives

Enter a Search String

Special character and space not allowed in the query term. Search string should be at least 2 characters long.

Reaction List for CamKII

Entries are grouped according to Reaction Name and they are alternately color coded using

and

color.
Further ordering can be done to the table header.

indicates that ordering is done according to ascending or descending order.
Keq is calculated only for first order reactions.
Kd is calculated only for second order reactions. [nA+nB <->nC or nA<->nC+nD, where n is number and A,B,C,D are molecules]

	Reaction Name	Accession Name / Accession No.	Pathway Name / Pathway No.	Kf	Kb	Kd	tau	Reagents
1	CaMKII-bind-CaM- PSD	CaMKII_noPKA_ model3 Accession No. 62	Shared_Object_ CaMKII_noPKA_ model3 Pathway No. 257	49.9998 (uM^-1 s^-1)	0 (s^-1)	-	-	Substrate: CaMKII-PSD CaM-Ca4-PSD Products: CaMKII-CaM-PSD
2	CaMKII-thr286-bi nd-CaM-PSD	CaMKII_noPKA_ model3 Accession No. 62	Shared_Object_ CaMKII_noPKA_ model3 Pathway No. 257	1000.02 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 0.0001(uM)	-	Substrate: CaMKII-thr286-PS D CaM-Ca4-PSD Products: CaMKII-thr286-Ca M-PSD
	Same values as for the main compartment Can the main compartment pool of Ca/CaM be used?
3	CaMKII-diss-CaM	CaMKII_noPKA_ model3 Accession No. 62	Shared_Object_ CaMKII_noPKA_ model3 Pathway No. 257	5 (s^-1)	0 (uM^-1 s^-1)	-	-	Substrate: CaMKII-CaM-PSD Products: CaM-Ca4-PSD CaMKII-PSD
4	Stoch_Basal_ CaMKII_PSD	CaMKII_noPKA_ model3 Accession No. 62	Shared_Object_ CaMKII_noPKA_ model3 Pathway No. 257	1 (s^-1)	1 (s^-1)	Keq = 1(uM)	0.5sec	Substrate: basal_CaMKII_ PSD_control Products: basal_CaMKII_ PSD
5	CaMKII-bind-CaM- PSD	CaMKII_model3 Accession No. 63	Shared_Object_ CaMKII_model3 Pathway No. 263	49.9998 (uM^-1 s^-1)	0 (s^-1)	-	-	Substrate: CaMKII-PSD CaM-Ca4-PSD Products: CaMKII-CaM-PSD
6	CaMKII-thr286-bi nd-CaM-PSD	CaMKII_model3 Accession No. 63	Shared_Object_ CaMKII_model3 Pathway No. 263	1000.02 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 0.0001(uM)	-	Substrate: CaMKII-thr286-PS D CaM-Ca4-PSD Products: CaMKII-thr286-Ca M-PSD
	Same values as for the main compartment Can the main compartment pool of Ca/CaM be used?
7	CaMKII-diss-CaM	CaMKII_model3 Accession No. 63	Shared_Object_ CaMKII_model3 Pathway No. 263	5 (s^-1)	0 (uM^-1 s^-1)	-	-	Substrate: CaMKII-CaM-PSD Products: CaM-Ca4-PSD CaMKII-PSD
8	Stoch_Basal_ CaMKII_PSD	CaMKII_model3 Accession No. 63	Shared_Object_ CaMKII_model3 Pathway No. 263	1 (s^-1)	1 (s^-1)	Keq = 1(uM)	0.5sec	Substrate: basal_CaMKII_ PSD_control Products: basal_CaMKII_ PSD
9	dephosp_CaMKIII	CaMKIII Accession No. 90	Shared_Object_ CaMKIII Pathway No. 1093	0.07 (s^-1)	0 (s^-1)	-	-	Substrate: CaMKIII* Products: CaMKIII
10	CaMKIII_bind_ CaM-Ca4	CaMKIII Accession No. 90	Shared_Object_ CaMKIII Pathway No. 1093	99 (uM^-1 s^-1)	0.09 (s^-1)	Kd(bf) = 0.0009(uM)	-	Substrate: CaM-Ca4 CaMKIII Products: CaMKIII_CaM-Ca4
11	CaMKII-bind-CaM- PSD	AMPAR_CaMKII_ strong_coupling Accession No. 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. 271	49.9998 (uM^-1 s^-1)	0 (s^-1)	-	-	Substrate: CaMKII-PSD CaM-Ca4-PSD Products: CaMKII-CaM-PSD
12	CaMKII-thr286-bi nd-CaM-PSD	AMPAR_CaMKII_ strong_coupling Accession No. 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. 271	1000.02 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 0.0001(uM)	-	Substrate: CaMKII-thr286-PS D CaM-Ca4-PSD Products: CaMKII-thr286-Ca M-PSD
	Same values as for the main compartment Can the main compartment pool of Ca/CaM be used?
13	CaMKII-diss-CaM	AMPAR_CaMKII_ strong_coupling Accession No. 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. 271	5 (s^-1)	0 (uM^-1 s^-1)	-	-	Substrate: CaMKII-CaM-PSD Products: CaM-Ca4-PSD CaMKII-PSD
14	Stoch_Basal_ CaMKII_PSD	AMPAR_CaMKII_ strong_coupling Accession No. 64	Shared_Object_ AMPAR_CaMKII_ strong_coupling Pathway No. 271	1 (s^-1)	1 (s^-1)	Keq = 1(uM)	0.5sec	Substrate: basal_CaMKII_ PSD_control Products: basal_CaMKII_ PSD
15	Stoch_Basal_ CaMKII_PSD	AMPAR_CaMKII_ weak_coupling Accession No. 65	CaMKII_PSD Pathway No. 292	1 (s^-1)	1 (s^-1)	Keq = 1(uM)	0.5sec	Substrate: basal_CaMKII_ PSD_control Products: basal_CaMKII_ PSD
	This reaction comes into play when stochastic calculations are used. If we do not have a stochastic step here then the levels of basal_CaMKII_PSD are just a fixed number, which is probably not a good representation of stochasticity. Having a reaction for the basal activity ensures that the basal activity too exhibits some fluctuations.
16	CaMKII-diss-CaM	AMPAR_CaMKII_ weak_coupling Accession No. 65	CaMKII_PSD Pathway No. 292	5 (s^-1)	0 (uM^-1 s^-1)	-	-	Substrate: CaMKII-CaM-PSD Products: CaM-Ca4-PSD CaMKII-PSD
17	CaMKII-bind-CaM- PSD	AMPAR_CaMKII_ weak_coupling Accession No. 65	CaMKII_PSD Pathway No. 292	49.9998 (uM^-1 s^-1)	0 (s^-1)	-	-	Substrate: CaMKII-PSD CaM-Ca4-PSD Products: CaMKII-CaM-PSD
18	CaMKII-thr286-bi nd-CaM-PSD	AMPAR_CaMKII_ weak_coupling Accession No. 65	CaMKII_PSD Pathway No. 292	1000.02 (uM^-1 s^-1)	0.1 (s^-1)	Kd(bf) = 0.0001(uM)	-	Substrate: CaMKII-thr286-PS D CaM-Ca4-PSD Products: CaMKII-thr286-Ca M-PSD
	Same values as for the main compartment Can the main compartment pool of Ca/CaM be used?
19	CaMKII-bind-CaM	fig3_CaMKII Accession No. 2	CaMKII Pathway No. 13	49.9998 (uM^-1 s^-1)	5 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate: CaM-Ca4 CaMKII Products: CaMKII-CaM
20	CaMKII-bind-CaM	fig4_synapse Accession No. 3	CaMKII Pathway No. 26	49.9998 (uM^-1 s^-1)	5 (s^-1)	Kd(bf) = 0.1(uM)	-	Substrate: CaM-Ca4 CaMKII Products: CaMKII-CaM

Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
This Copyright is applied to ensure that the contents of this database remain freely available. Please see FAQ for details.