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Pathway List for pka
Result: 1 - 14 of 14 rows are displayed
Default ordering is done according to Pathway Name.Table header can be used for changing the default ordering.
indicates that ordering is done according to ascending or descending order.
Entries are color tagged depending on Network  or Pathway 
  Pathway Name
Pathway No.		Accession Name
Accession No.		Accession
Type		Pathway statisticspka statisticsSource
Entry Date
1 PKA
Pathway No. 17		 fig3_CaMKII

Accession No. 2		NetworkMolecule = 9
Enzyme   = 0
Reaction  = 7
Molecule = 0
Enzyme   = 0
Reaction  = 0
Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/
2001-11-07 00:00:00
   Related Pathway: 
30, 84, 135, 196, 220, 240, 250, 270, 277, 288, 326, 343, 361
    This is the model file for figure 3 from Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. It is a model of the Ca activation of CaMKII and other CaM-activated enzymes. It includes the regulatory phosphatases PP1 and PP2B (Calcineurin) acting on CaMKII and also includes CaM-activated adenylyl cyclase and PKA in the synapse.
Demonstration script files for generating the figures in the paper, including figure 3, are available here.
   
This pathway is part of accession 2 and is completely specified in the file acc2.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc2.g   
GENESIS Format (Annotated version)    Anno_acc2.g   
2 PKA
Pathway No. 30		 fig4_synapse

Accession No. 3		NetworkMolecule = 9
Enzyme   = 0
Reaction  = 7
Molecule = 0
Enzyme   = 0
Reaction  = 0
Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/
2001-11-07 00:00:00
   Related Pathway: 
17, 84, 135, 196, 220, 240, 250, 270, 277, 288, 326, 343, 361
    This is the composite model of 4 kinases: PKC, MAPK, PKA and CaMKII and numerous regulatory pathways involved in synaptic signaling. From Bhalla US and Iyengar R. Science (1999) 283(5400):381-7.This model comes from figure 4 of that paper.
Demonstration script files for generating the figures in the paper, including figure 4, are available here.
   
This pathway is part of accession 3 and is completely specified in the file acc3.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc3.g   
GENESIS Format (Annotated version)    Anno_acc3.g   
3 PKA
Pathway No. 84		 Synaptic_
Network
Accession No. 16		NetworkMolecule = 9
Enzyme   = 0
Reaction  = 7
Molecule = 0
Enzyme   = 0
Reaction  = 0
Bhalla US and Iyengar R. Science (1999) 283(5400):381-7. ( peer-reviewed publication )/
2001-12-12 00:00:00
   Related Pathway: 
17, 30, 135, 196, 220, 240, 250, 270, 277, 288, 326, 343, 361
    Protein kinase A. It has two regulatory and two catalytic subunits, represented here as R2C2. Each regulatory subunit binds two cAMPs. I also model an inhibitor of PKA which binds stoichiometrically and thus sharpens the response curve for PKA against cAMP. General reference: Taylor et al Ann Rev Biochem 1990 59:971-1005 Other references Ogreid and Doskeland 1983 Biochem 22:1686-1696 is a great, detailed paper. Also: Ogreid and Doskeland 1982 FEBS Lett 150(1):161-166 Ogreid et al 1983 JBC 258(2):1041-1049 Robinson-Steiner and Corbin 1983 JBC 258(2):1032-1040 Hasler et al 1992 FASEB J 6:2735-2741
   
This pathway is part of accession 16 and is completely specified in the file acc16.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc16.g   
GENESIS Format (Annotated version)    Anno_acc16.g   
4 PKA
Pathway No. 135		 cAMP_pathway

Accession No. 25		NetworkMolecule = 9
Enzyme   = 0
Reaction  = 7
Molecule = 0
Enzyme   = 0
Reaction  = 0
Bhalla US Methods Enzymol. 2002;345:3-23). ( peer-reviewed publication )/
2002-01-12 00:00:00
   Related Pathway: 
17, 30, 84, 196, 220, 240, 250, 270, 277, 288, 326, 343, 361
    General ref: Taylor et al Ann Rev Biochem 1990 59:971-1005
   
FormatFile
Native Format (GENESIS format)    path135.g   
GENESIS Format (Annotated version)    Anno_path135.g   
MATLAB format    path135.m   
5 PKA
Pathway No. 196		 PKA_2003

Accession No. 47		NetworkMolecule = 9
Enzyme   = 0
Reaction  = 7
Molecule = 0
Enzyme   = 0
Reaction  = 0
Bhalla US. (2004) Biophys J. 87(2):733-44. ( peer-reviewed publication )/
2003-04-28 00:00:00
   Related Pathway: 
17, 30, 84, 135, 220, 240, 250, 270, 277, 288, 326, 343, 361
    General ref: Taylor et al Ann Rev Biochem 1990 59:971-1005
   
FormatFile
Native Format (GENESIS format)    path196.g   
GENESIS Format (Annotated version)    Anno_path196.g   
MATLAB format    path196.m   
6 PKA
Pathway No. 220		 MAPK_network_
2003
Accession No. 50		NetworkMolecule = 9
Enzyme   = 0
Reaction  = 7
Molecule = 0
Enzyme   = 0
Reaction  = 0
Bhalla US Biophys J. 2004 Aug;87(2):745-53. ( peer-reviewed publication )/
2003-04-28 00:00:00
   Related Pathway: 
17, 30, 84, 135, 196, 240, 250, 270, 277, 288, 326, 343, 361
    General ref: Taylor et al Ann Rev Biochem 1990 59:971-1005
   
FormatFile
Native Format (GENESIS format)    path220.g   
GENESIS Format (Annotated version)    Anno_path220.g   
MATLAB format    path220.m   
7 PKA
Pathway No. 240		 AMPAR_traff_
model0
Accession No. 59		NetworkMolecule = 10
Enzyme   = 35
Reaction  = 7
Molecule = 0
Enzyme   = 1
Reaction  = 0
Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
2005-07-19 00:00:00
   Related Pathway: 
17, 30, 84, 135, 196, 220, 250, 270, 277, 288, 326, 343, 361
    General ref: Taylor et al Ann Rev Biochem 1990 59:971-1005
   
This pathway is part of accession 59 and is completely specified in the file acc59.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc59.g   
MATLAB format    acc59.m   
SBML format    acc59.xml   
8 PKA
Pathway No. 250		 AMPAR_traff_
model1
Accession No. 60		NetworkMolecule = 10
Enzyme   = 35
Reaction  = 7
Molecule = 0
Enzyme   = 1
Reaction  = 0
Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
2005-07-19 00:00:00
   Related Pathway: 
17, 30, 84, 135, 196, 220, 240, 270, 277, 288, 326, 343, 361
    General ref: Taylor et al Ann Rev Biochem 1990 59:971-1005
   
This pathway is part of accession 60 and is completely specified in the file acc60.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc60.g   
MATLAB format    acc60.m   
SBML format    acc60.xml   
9 PKA
Pathway No. 270		 CaMKII_model3

Accession No. 63		NetworkMolecule = 9
Enzyme   = 0
Reaction  = 7
Molecule = 0
Enzyme   = 0
Reaction  = 0
Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
2005-07-19 00:00:00
   Related Pathway: 
17, 30, 84, 135, 196, 220, 240, 250, 277, 288, 326, 343, 361
    This is the complete model of CaMKII bistability, model 3. It exhibits bistability in CaMKII activation due to autophosphorylation at the PSD and local saturation of PP1. This version of model 3 includes PKA regulatory input. This has little effect on the deterministic calculations, but the PKA pathway introduces a lot of noise which causes a difference in stochastic runs.
   
This pathway is part of accession 63 and is completely specified in the file acc63.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc63.g   
MATLAB format    acc63.m   
SBML format    acc63.xml   
10 PKA
Pathway No. 277		 AMPAR_CaMKII_
strong_coupling
Accession No. 64		NetworkMolecule = 9
Enzyme   = 0
Reaction  = 7
Molecule = 0
Enzyme   = 0
Reaction  = 0
Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
2005-07-19 00:00:00
   Related Pathway: 
17, 30, 84, 135, 196, 220, 240, 250, 270, 288, 326, 343, 361
    General ref: Taylor et al Ann Rev Biochem 1990 59:971-1005
   
This pathway is part of accession 64 and is completely specified in the file acc64.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc64.g   
MATLAB format    acc64.m   
SBML format    acc64.xml   
11 PKA
Pathway No. 288		 AMPAR_CaMKII_
weak_coupling
Accession No. 65		NetworkMolecule = 10
Enzyme   = 35
Reaction  = 7
Molecule = 0
Enzyme   = 1
Reaction  = 0
Hayer A, Bhalla US PLoS Comput Biol. 2005 Jul;1(2):137-54. Epub 2005 Jul 29. ( Peer-reviewed publication )/
2005-07-21 00:00:00
   Related Pathway: 
17, 30, 84, 135, 196, 220, 240, 250, 270, 277, 326, 343, 361
    General ref: Taylor et al Ann Rev Biochem 1990 59:971-1005
   
This pathway is part of accession 65 and is completely specified in the file acc65.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc65.g   
MATLAB format    acc65.m   
SBML format    acc65.xml   
12 PKA
Pathway No. 326		 Ajay_Bhalla_
2004_PKM_Tuning
Accession No. 76		NetworkMolecule = 9
Enzyme   = 0
Reaction  = 7
Molecule = 0
Enzyme   = 0
Reaction  = 0
Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. ( Peer-reviewed publication )/
2006-12-12 00:00:00
   Related Pathway: 
17, 30, 84, 135, 196, 220, 240, 250, 270, 277, 288, 343, 361
    General ref: Taylor et al Ann Rev Biochem 1990 59:971-1005
   
This pathway is part of accession 76 and is completely specified in the file acc76.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc76.g   
MATLAB format    acc76.m   
SBML format    acc76.xml   
13 PKA
Pathway No. 343		 Ajay_Bhalla_
2004_PKM_MKP3_
Tuning
Accession No. 77		NetworkMolecule = 9
Enzyme   = 0
Reaction  = 7
Molecule = 0
Enzyme   = 0
Reaction  = 0
Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80 ( Peer-reviewed publication )/
2006-12-12 00:00:00
   Related Pathway: 
17, 30, 84, 135, 196, 220, 240, 250, 270, 277, 288, 326, 361
    General ref: Taylor et al Ann Rev Biochem 1990 59:971-1005
   
This pathway is part of accession 77 and is completely specified in the file acc77.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc77.g   
MATLAB format    acc77.m   
SBML format    acc77.xml   
14 PKA
Pathway No. 361		 Ajay_Bhalla_
2004_Feedback_
Tuning
Accession No. 78		NetworkMolecule = 9
Enzyme   = 0
Reaction  = 7
Molecule = 0
Enzyme   = 0
Reaction  = 0
Ajay SM, Bhalla US. Eur J Neurosci. 2004 Nov;20(10):2671-80. ( Peer-reviewed publication )/
2006-12-12 00:00:00
   Related Pathway: 
17, 30, 84, 135, 196, 220, 240, 250, 270, 277, 288, 326, 343
    General ref: Taylor et al Ann Rev Biochem 1990 59:971-1005
   
This pathway is part of accession 78 and is completely specified in the file acc78.g.
There is no separate files for just this pathway.
FormatFile
Native Format (GENESIS format)    acc78.g   
MATLAB format    acc78.m   
SBML format    acc78.xml